Description |
large tumor suppressor kinase 2 |
MDM4 regulator of p53 |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- 3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134)
- Refractive error ( 32231278)
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- Breast cancer ( 23535733 27117709)
- Breast cancer (estrogen-receptor negative) ( 27117709 29058716)
- Breast cancer (estrogen-receptor negative, progesterone-receptor negative, and human epidermal growth factor-receptor negative) ( 24325915)
- Breast Cancer in BRCA1 mutation carriers ( 23544013)
- Cognitive performance ( 19734545)
- Diastolic blood pressure ( 27618452 30578418)
- Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
- Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
- Eosinophil counts ( 32888494)
- Eosinophil percentage of white cells ( 32888494)
- Fish- and plant-related diet ( 32066663)
- Glioma ( 28346443)
- Levodopa wearing off effect (time symptoms uncontrolled) in Parkinson's disease (response to zonisamide) ( 32355309)
- Non-glioblastoma glioma ( 28346443)
- Oily fish consumption ( 32066663)
- Pork consumption ( 32066663)
- Prostate cancer ( 23535732)
- Regular attendance at a religious group ( 29970889)
- Systolic blood pressure ( 27618452)
- Type 2 diabetes ( 32499647)
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Interacting Genes |
67 interacting genes:
ABL1
AJUBA
AKT1
ARAF
ARNT
AURKA
AURKB
BECN1
BRAF
CBLC
CCND2
CCNE1
CD44
CDK2
CDK4
CDK6
CDKN1A
CDKN2A
CDKN2B
CDKN2C
CHEK1
CHEK2
CTNNB1
DYRK1A
EPHA2
ERBB2
EZH2
FGFR4
FHL3
FZR1
GLIS1
GLIS2
GRAP2
GRM1
HGF
HIF1A
KAT2A
KDELR2
KIF23
MAP2K3
MAP2K5
MAPK14
MDM4
MET
MOB3A
MOB3B
MOB3C
MOB4
MYC
NF2
NFIC
PDGFRA
RAF1
RASSF1
RELA
SMAD2
SNAI1
STK11
STK3
SUZ12
TAZ
TEAD2
TP53
TSC1
WWTR1
YWHAG
YWHAZ
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63 interacting genes:
AKT1
APP
ARF1
ATM
BECN1
C1orf109
CAPN7
CASP3
CBLC
CD160
CD44
CDK1
CDK4
CDKN2A
CDKN2B
CHEK1
CHEK2
CSNK1A1
E2F1
EP300
EPHA2
FGFR4
GLIS2
HGF
LATS2
LRSAM1
MAGEA1
MAP2K5
MDM2
MKRN3
MNAT1
NAA10
NF2
PELI1
PRKAA1
RAD54B
RB1
RNF115
S100B
SFN
SMAD3
SMAD4
SMARCA2
TP53
TP63
TP73
TRIM46
TRIM55
UBC
UBE2D1
UBE2D2
UBE2D3
USP7
VPS26C
WDR5
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
ZKSCAN3
ZKSCAN4
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Entrez ID |
26524 |
4194 |
HPRD ID |
07277 |
04082 |
Ensembl ID |
ENSG00000150457
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ENSG00000198625
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Uniprot IDs |
A0A024RDM3
Q9NRM7
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A0A087WTR9
A0A087WUE3
A0A087WZ58
O15151
Q59FS6
Q68DC0
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PDB IDs |
4ZRI
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2CR8
2MWY
2N06
2N0U
2N0W
2N14
2VJE
2VJF
2VYR
3DAB
3EQY
3FDO
3FE7
3FEA
3JZO
3JZP
3JZQ
3LBJ
3MQR
3U15
4RXZ
5MNJ
5UML
5VK1
6Q9Q
6Q9S
6Q9U
6Q9W
6Q9Y
7C3Q
7C3Y
7C44
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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