HSPB8 and FAM214B

Data Source:
BioGRID (two hybrid)

		HSPB8	FAM214B
Description		heat shock protein family B (small) member 8	family with sequence similarity 214 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body Chaperone Complex	Nucleus
	Molecular Function	Protein Kinase Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Protein Phosphorylation Cellular Response To Unfolded Protein Regulation Of Cellular Response To Heat Positive Regulation Of Aggrephagy
Pathways		HSF1-dependent transactivation
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy Distal hereditary motor neuropathies (dHMN)
GWAS		Metabolite levels ( 23823483) PR interval in Tripanosoma cruzi seropositivity ( 24324551)
Interacting Genes		22 interacting genes: ATXN7L2 BAG3 C2CD6 CRYAB CSNK2A1 DUSP12 FAM214B HSPB1 HSPB2 HSPB3 HSPB6 HSPB7 MAPK3 MISP MLF2 PRKCA QRICH1 RPIA SLC16A5 SNCA SOCS7 TRAPPC6A	63 interacting genes: ABI2 AKAP8L APP BAG4 BHLHB9 C11orf65 C7orf57 CALCOCO2 CCDC125 CCDC33 CCDC85B CEP70 CYSRT1 DIP2A DNAJA3 EFHC2 EYA2 FHL2 FHL5 GOLGA2 HSF2BP HSPB8 IKZF1 KIF20A KPNA3 KPNA5 KRT34 KRTAP19-5 KRTAP19-6 KRTAP6-2 KRTAP6-3 LMO2 LZTS2 MDFI MID2 MKRN3 MYO1F MYO5B MYOZ3 NCOA5 PDLIM7 PFDN5 PICK1 PRDM6 PTPN21 RBM11 SFMBT1 SLAIN1 SORBS3 TBC1D23 TEPSIN TLE5 TRAF2 TRAF4 TRIM27 VPS9D1 WWOX WWP2 ZMYND12 ZNF219 ZNF572 ZNF655 ZRANB1
Entrez ID		26353	80256
HPRD ID		06420	13869
Ensembl ID		ENSG00000152137	ENSG00000005238
Uniprot IDs		Q9UJY1	Q7L5A3
PDB IDs
Enriched GO Terms of Interacting Partners?
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