HSPB8 and HSPB7

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid)
HPRD (two hybrid)

		HSPB8	HSPB7
Description		heat shock protein family B (small) member 8	heat shock protein family B (small) member 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body Chaperone Complex	Nucleus Nucleoplasm Cytoplasm Cajal Body Aggresome
	Molecular Function	Protein Kinase Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding Protein C-terminus Binding
	Biological Process	Protein Phosphorylation Cellular Response To Unfolded Protein Regulation Of Cellular Response To Heat Positive Regulation Of Aggrephagy	Response To Unfolded Protein Heart Development Regulation Of Heart Contraction
Pathways		HSF1-dependent transactivation
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy Distal hereditary motor neuropathies (dHMN)
GWAS		Metabolite levels ( 23823483) PR interval in Tripanosoma cruzi seropositivity ( 24324551)	Arterial stiffness index ( 31235810) Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Erectile dysfunction ( 30583798) Systolic blood pressure ( 28739976)
Interacting Genes		22 interacting genes: ATXN7L2 BAG3 C2CD6 CRYAB CSNK2A1 DUSP12 FAM214B HSPB1 HSPB2 HSPB3 HSPB6 HSPB7 MAPK3 MISP MLF2 PRKCA QRICH1 RPIA SLC16A5 SNCA SOCS7 TRAPPC6A	19 interacting genes: APP BAG3 C22orf15 CEP76 DDIT4L DYNLT1 FLNA GUCD1 HSPB8 PDLIM7 PIP4K2B PLEKHF2 PRDM14 REL SF3B4 SYCE1 TCF4 TEPSIN TRIM23
Entrez ID		26353	27129
HPRD ID		06420	13684
Ensembl ID		ENSG00000152137	ENSG00000173641
Uniprot IDs		Q9UJY1	Q9UBY9
PDB IDs
Enriched GO Terms of Interacting Partners?
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