HSPB8 and HSPB6

Data Source:
HPRD (in vivo, two hybrid)

		HSPB8	HSPB6
Description		heat shock protein family B (small) member 8	heat shock protein family B (small) member 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body Chaperone Complex	Extracellular Region Nucleus Nucleolus Cytoplasm Golgi Apparatus Cytosol
	Molecular Function	Protein Kinase Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity	Structural Constituent Of Eye Lens Protein Binding Protein Homodimerization Activity Unfolded Protein Binding Chaperone Binding
	Biological Process	Protein Phosphorylation Cellular Response To Unfolded Protein Regulation Of Cellular Response To Heat Positive Regulation Of Aggrephagy	Regulation Of Muscle Contraction Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Angiogenesis Chaperone-mediated Protein Folding
Pathways		HSF1-dependent transactivation
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy Distal hereditary motor neuropathies (dHMN)
GWAS		Metabolite levels ( 23823483) PR interval in Tripanosoma cruzi seropositivity ( 24324551)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		22 interacting genes: ATXN7L2 BAG3 C2CD6 CRYAB CSNK2A1 DUSP12 FAM214B HSPB1 HSPB2 HSPB3 HSPB6 HSPB7 MAPK3 MISP MLF2 PRKCA QRICH1 RPIA SLC16A5 SNCA SOCS7 TRAPPC6A	4 interacting genes: CRYAB HSPB8 SNCA YWHAG
Entrez ID		26353	126393
HPRD ID		06420	08130
Ensembl ID		ENSG00000152137	ENSG00000004776
Uniprot IDs		Q9UJY1	O14558 V9HWB6
PDB IDs			4JUS 4JUT 5LTW 5LU1 5LU2 5LUM 5OK9 5OKF
Enriched GO Terms of Interacting Partners?
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