HSPB6 and HSPB8

Data Source:
HPRD (in vivo, two hybrid)

		HSPB6	HSPB8
Description		heat shock protein family B (small) member 6	heat shock protein family B (small) member 8
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleolus Cytoplasm Golgi Apparatus Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body Chaperone Complex
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Protein Homodimerization Activity Unfolded Protein Binding Chaperone Binding	Protein Kinase Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Regulation Of Muscle Contraction Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Angiogenesis Chaperone-mediated Protein Folding	Protein Phosphorylation Cellular Response To Unfolded Protein Regulation Of Cellular Response To Heat Positive Regulation Of Aggrephagy
Pathways			HSF1-dependent transactivation
Drugs
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy Distal hereditary motor neuropathies (dHMN)
GWAS		Brain morphology (MOSTest) ( 32665545)	Metabolite levels ( 23823483) PR interval in Tripanosoma cruzi seropositivity ( 24324551)
Interacting Genes		4 interacting genes: CRYAB HSPB8 SNCA YWHAG	22 interacting genes: ATXN7L2 BAG3 C2CD6 CRYAB CSNK2A1 DUSP12 FAM214B HSPB1 HSPB2 HSPB3 HSPB6 HSPB7 MAPK3 MISP MLF2 PRKCA QRICH1 RPIA SLC16A5 SNCA SOCS7 TRAPPC6A
Entrez ID		126393	26353
HPRD ID		08130	06420
Ensembl ID		ENSG00000004776	ENSG00000152137
Uniprot IDs		O14558 V9HWB6	Q9UJY1
PDB IDs		4JUS 4JUT 5LTW 5LU1 5LU2 5LUM 5OK9 5OKF
Enriched GO Terms of Interacting Partners?
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