FAM161B and SPDEF

Data Source:
BioGRID (two hybrid)

		FAM161B	SPDEF
Description		FAM161 centrosomal protein B	SAM pointed domain containing ETS transcription factor
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasmic Microtubule Cilium Microtubule Cytoskeleton	Chromatin Nucleus
	Molecular Function	Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Biological_process Cilium Organization	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Negative Regulation Of Cell Fate Commitment Positive Regulation Of Cell Fate Commitment Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Lung Goblet Cell Differentiation Intestinal Epithelial Cell Development
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Serum uric acid levels ( 29559957)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Height ( 28552196) Inflammatory bowel disease ( 27569725) Refractive error ( 32231278) Weight ( 28552196)
Interacting Genes		70 interacting genes: ABI2 BICD2 BLOC1S2 BORCS6 CARD9 CBY1 CCDC125 CCDC13 CCDC136 CCDC138 CCDC172 CCDC57 CCDC83 CCDC88B CDR2L CEP55 CEP70 CINP CTNNA3 DDI1 EXOSC8 GAS8 GOLGA2 GOLGA6A GOLGA6L9 GPSM1 HAUS1 HOMER3 HOOK2 HSF2BP ISY1-RAB43 KIAA1328 LZTS1 MAPRE3 MDFI MEIS3 MID2 MIPOL1 MTUS2 NDUFB7 NECAB2 NR3C1 OIP5 PICK1 PLAGL2 PNMA1 PPP2R3C RINT1 SH3BP5L SMAD2 SPDEF SRGAP2B STX11 STX1B SYCE1 TEX11 TEX12 TFIP11 TRAF1 TRAF2 TRIM15 TSGA10 TSNAXIP1 TTC23 TTC23L USH1G USHBP1 VPS52 ZC4H2 ZRANB1	12 interacting genes: AR CEP57 COX5A ENKD1 FAM161B NKX3-1 PCGF2 PSMA1 SNX20 SRPK2 STK11 TTC23
Entrez ID		145483	25803
HPRD ID		12649	12176
Ensembl ID		ENSG00000156050	ENSG00000124664
Uniprot IDs		Q96MY7	O95238
PDB IDs			1YO5 2DKX
Enriched GO Terms of Interacting Partners?
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