SPAG8 and RBP3

Data Source:
BioGRID (two hybrid)

		SPAG8	RBP3
Description		sperm associated antigen 8	retinol binding protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Cytoplasm Spindle Membrane	Extracellular Region Extracellular Space Cone Matrix Sheath Extracellular Vesicle
	Molecular Function	Molecular_function Protein Binding Microtubule Binding	Retinoid Binding Protein Binding Serine-type Peptidase Activity Retinal Binding Retinol Binding
	Biological Process	Cell Cycle Spermatogenesis Single Fertilization Biological_process Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Retinoid Metabolic Process Proteolysis Lipid Metabolic Process Visual Perception
Pathways			The retinoid cycle in cones (daylight vision) The canonical retinoid cycle in rods (twilight vision)
Drugs			Lapachone
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545)	Corneal curvature ( 24963161) Macular thickness ( 30535121)
Interacting Genes		87 interacting genes: ARMC5 B9D2 BATF2 C19orf54 CARM1 CCDC120 CCNC CDC23 CFP CSTF2 CSTF2T CTAG1A CTAG1B DMRT3 DOK3 DTX2 DYNLL2 EGFL7 FAM168B GIGYF1 GLYCTK GPSM3 HR INCA1 INTS11 JMJD4 KDM3B KLHL32 KRT34 KRTAP10-8 KRTAP11-1 KRTAP13-3 KRTAP15-1 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP26-1 KRTAP3-1 KRTAP6-2 KRTAP7-1 LASP1 MEOX1 METTL15 MGAT5B NEDD4L NHLRC4 NSD3 NUDT21 PATZ1 PEF1 PFDN5 PHF1 PITX1 PLA2G10 PRMT1 PRMT2 PRMT5 PRR35 RAN RBP3 RIPK4 RNF125 RUSC1 SERGEF SMUG1 SMYD1 SNRPB SNRPC SYNGAP1 TEKT3 TEKT5 TENT5B TRIB3 TRIM42 TSC1 TTC23 UBAP2 UBQLN1 UBQLN4 USP2 VPS37C YPEL3 ZBTB32 ZIC1 ZNF34 ZNF581	15 interacting genes: CDC23 CREB5 CYSRT1 EFEMP2 HOXA1 HR HSD3B7 KPRP KRTAP10-5 MGAT5B NID2 NOTCH1 PLSCR4 POU4F2 SPAG8
Entrez ID		26206	5949
HPRD ID		12039	01581
Ensembl ID		ENSG00000137098	ENSG00000265203
Uniprot IDs		A0A140VJV0 Q99932	P10745
PDB IDs
Enriched GO Terms of Interacting Partners?
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