SPAG8 and CSTF2

Data Source:
BioGRID (two hybrid, two hybrid)

		SPAG8	CSTF2
Description		sperm associated antigen 8	cleavage stimulation factor subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Cytoplasm Spindle Membrane	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Nuclear Body Cleavage Body
	Molecular Function	Molecular_function Protein Binding Microtubule Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	Cell Cycle Spermatogenesis Single Fertilization Biological_process Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA 3'-end Processing Pre-mRNA Cleavage Required For Polyadenylation
Pathways			tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		87 interacting genes: ARMC5 B9D2 BATF2 C19orf54 CARM1 CCDC120 CCNC CDC23 CFP CSTF2 CSTF2T CTAG1A CTAG1B DMRT3 DOK3 DTX2 DYNLL2 EGFL7 FAM168B GIGYF1 GLYCTK GPSM3 HR INCA1 INTS11 JMJD4 KDM3B KLHL32 KRT34 KRTAP10-8 KRTAP11-1 KRTAP13-3 KRTAP15-1 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP26-1 KRTAP3-1 KRTAP6-2 KRTAP7-1 LASP1 MEOX1 METTL15 MGAT5B NEDD4L NHLRC4 NSD3 NUDT21 PATZ1 PEF1 PFDN5 PHF1 PITX1 PLA2G10 PRMT1 PRMT2 PRMT5 PRR35 RAN RBP3 RIPK4 RNF125 RUSC1 SERGEF SMUG1 SMYD1 SNRPB SNRPC SYNGAP1 TEKT3 TEKT5 TENT5B TRIB3 TRIM42 TSC1 TTC23 UBAP2 UBQLN1 UBQLN4 USP2 VPS37C YPEL3 ZBTB32 ZIC1 ZNF34 ZNF581	49 interacting genes: ABHD11 AKAP8L ANKRD10 APP ATP23 BAG6 CDSN CEACAM6 CEP126 CHD3 CNOT2 CSTF3 CTBP2 DDX1 ECH1 EEF1G ELP1 ERG28 FAM168B FEZ1 HDHD3 HGS IMMT INCA1 KAT5 METTL15 METTL27 MIR19A MIR92A2 POLR2A POU6F2 PPP1R32 PRDM6 RFX6 SPAG8 SS18L1 STH SUB1 SYMPK TFG TLE3 TLE5 TSC1 UBQLN1 UBQLN2 UBQLN4 UFSP1 USP54 ZNF341
Entrez ID		26206	1478
HPRD ID		12039	02652
Ensembl ID		ENSG00000137098	ENSG00000101811
Uniprot IDs		A0A140VJV0 Q99932	B3V096 B4DUD5 E7EWR4 P33240
PDB IDs			1P1T 2J8P 6Q2I 6TZE
Enriched GO Terms of Interacting Partners?
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