INTS7 and CA8

Data Source:
BioGRID (two hybrid)

		INTS7	CA8
Description		integrator complex subunit 7	carbonic anhydrase 8
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytoplasm Nuclear Body Integrator Complex	Cytoplasm
	Molecular Function	Protein Binding	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding Hydro-lyase Activity
	Biological Process	DNA Damage Checkpoint SnRNA Processing SnRNA 3'-end Processing SnRNA Transcription By RNA Polymerase II Cellular Response To Ionizing Radiation	One-carbon Metabolic Process Phosphatidylinositol-mediated Signaling
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs			Zonisamide
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hip circumference adjusted for BMI ( 25673412) Temperament (bipolar disorder) ( 22365631) Urate levels ( 31578528)	Adult body size ( 32376654) Blood protein levels ( 30072576) Cardiac hypertrophy ( 21348951) Free thyroxine concentration ( 30367059) Height ( 31562340) Hemoglobin ( 32888494) Myopia ( 27182965) Obesity-related traits ( 23251661) Parkinson's disease ( 27182965) Red blood cell count ( 32888494) Refractive error ( 32231278) Response to amphetamines ( 22952603) Schizophrenia ( 28991256 25056061 29483656 30285260) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		4 interacting genes: CA8 CTDP1 FBXO7 PAXIP1	14 interacting genes: CRX GGA2 HSD17B14 INTS7 ITPR1 KLHL8 LMNB2 LNX1 LRCH4 MAGED1 RAB34 SPDL1 STAT3 TBX3
Entrez ID		25896	767
HPRD ID		08522	00266
Ensembl ID		ENSG00000143493	ENSG00000178538
Uniprot IDs		Q9NVH2	P35219
PDB IDs			2W2J
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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