LSM4 and RHOXF2

Data Source:
BioGRID (two hybrid)

		LSM4	RHOXF2
Description		LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated	Rhox homeobox family member 2
Image			No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm U6 SnRNP Cytosol Membrane Protein-containing Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Spliceosomal Tri-snRNP Complex Lsm2-8 Complex	Chromatin Nucleus
	Molecular Function	RNA Binding Protein Binding U6 SnRNA Binding PH Domain Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing P-body Assembly Exonucleolytic Catabolism Of Deadenylated MRNA	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Chronotype ( 30696823) Estimated glomerular filtration rate ( 30604766) Gastroesophageal reflux disease ( 31527586) Intraocular pressure ( 29617998) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet distribution width ( 32888494) Red blood cell count ( 32888494 27863252) Reticulocyte count ( 32888494)
Interacting Genes		21 interacting genes: CALCOCO2 COX5B EXOSC8 GAS7 HOMEZ IKZF1 L3MBTL3 LSM7 NMI PLEKHA5 PSTPIP1 RHOXF2 SLC22A2 SMIM14 SMN1 SMU1 SNRPE TOE1 TOP1 XRN1 ZBTB10	101 interacting genes: ARID5A ARMCX2 ARSA ATN1 ATXN1 BATF3 BOLL C1orf94 CAMK2A CCDC33 CCNK CEACAM6 CERCAM CHAC1 CLASRP CLDN7 CREM CRX CRYBA1 DAB1 DAZAP2 DEDD2 DTX2 DVL2 EFEMP2 EWSR1 FAM166A FAM168A FAM168B FBF1 HNRNPLL HOXC13 HYPK KHDC4 KLHDC7B KRTAP12-2 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP26-1 KRTAP6-1 KRTAP6-2 KRTAP7-1 LASP1 LENG8 LSM4 LZTS2 MAGED1 MDFI MED7 MGAT5B MSX2 MVP NANOG NEU4 NKX1-2 NKX3-1 PITX1 PLAC8 PLOD3 POLR3D POU2AF1 PRR20A PRR20B PRR20C PRR20D PRR20E PRR34 PSMF1 RADIL RAMAC RBFOX1 RBFOX2 RBM11 RBPMS RBPMS2 RNF4 SERF2 SNAPC1 SUMO1 TENT5A TENT5B TENT5C TENT5D TEP1 TLE5 TMCC2 TOLLIP TRIP13 UBAP2 UBE2I UPF1 UTP6 VAC14 VENTX VPS25 ZBTB32 ZNF683
Entrez ID		25804	84528
HPRD ID		06284	02345
Ensembl ID		ENSG00000130520	ENSG00000131721
Uniprot IDs		Q9Y4Z0 U3KQK1	Q9BQY4
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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