RHOXF2 and CHAC1

Data Source:
HPRD (two hybrid)

		RHOXF2	CHAC1
Description		Rhox homeobox family member 2	ChaC glutathione specific gamma-glutamylcyclotransferase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Cytoplasm Trans-Golgi Network Cytosol
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Gamma-glutamylcyclotransferase Activity Notch Binding Protein Binding Glutathione Specific Gamma-glutamylcyclotransferase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression	Glutathione Biosynthetic Process Glutathione Catabolic Process Response To Unfolded Protein Notch Signaling Pathway Negative Regulation Of Protein Processing Neurogenesis Negative Regulation Of Notch Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Pathways			Glutathione synthesis and recycling Response of EIF2AK1 (HRI) to heme deficiency
Drugs
Diseases
GWAS			FEV1 ( 30804560) Lung function (FVC) ( 30804560) Malaria ( 31844061) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		101 interacting genes: ARID5A ARMCX2 ARSA ATN1 ATXN1 BATF3 BOLL C1orf94 CAMK2A CCDC33 CCNK CEACAM6 CERCAM CHAC1 CLASRP CLDN7 CREM CRX CRYBA1 DAB1 DAZAP2 DEDD2 DTX2 DVL2 EFEMP2 EWSR1 FAM166A FAM168A FAM168B FBF1 HNRNPLL HOXC13 HYPK KHDC4 KLHDC7B KRTAP12-2 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP26-1 KRTAP6-1 KRTAP6-2 KRTAP7-1 LASP1 LENG8 LSM4 LZTS2 MAGED1 MDFI MED7 MGAT5B MSX2 MVP NANOG NEU4 NKX1-2 NKX3-1 PITX1 PLAC8 PLOD3 POLR3D POU2AF1 PRR20A PRR20B PRR20C PRR20D PRR20E PRR34 PSMF1 RADIL RAMAC RBFOX1 RBFOX2 RBM11 RBPMS RBPMS2 RNF4 SERF2 SNAPC1 SUMO1 TENT5A TENT5B TENT5C TENT5D TEP1 TLE5 TMCC2 TOLLIP TRIP13 UBAP2 UBE2I UPF1 UTP6 VAC14 VENTX VPS25 ZBTB32 ZNF683	1 interacting genes: RHOXF2
Entrez ID		84528	79094
HPRD ID		02345	14634
Ensembl ID		ENSG00000131721	ENSG00000128965
Uniprot IDs		Q9BQY4	Q9BUX1
PDB IDs
Enriched GO Terms of Interacting Partners?
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