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RHOXF2 and NKX3-1
Data Source:
BioGRID
(two hybrid)
RHOXF2
NKX3-1
Description
Rhox homeobox family member 2
NK3 homeobox 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Chromatin
Nucleus
Nucleoplasm
Cytosol
Site Of DNA Damage
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Sequence-specific Double-stranded DNA Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Nuclear Receptor Activity
Protein Binding
Transcription Factor Binding
Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
Estrogen Receptor Activity
Estrogen Receptor Binding
Histone Deacetylase Binding
Sequence-specific DNA Binding
Protein Self-association
MADS Box Domain Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Gene Expression
Metanephros Development
Somitogenesis
Positive Regulation Of Protein Phosphorylation
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Multicellular Organism Development
Salivary Gland Development
Heart Development
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Male Gonad Development
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of Cell Death
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Cell Differentiation
Androgen Receptor Signaling Pathway
Regulation Of Protein Localization
Response To Testosterone
Cellular Response To Drug
Dorsal Aorta Development
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Protein Kinase B Signaling
Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Mitotic Cell Cycle
Positive Regulation Of Mitotic Cell Cycle
Positive Regulation Of Transcription By RNA Polymerase II
Branching Morphogenesis Of An Epithelial Tube
Negative Regulation Of Epithelial Cell Proliferation
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Cell Division
Pharyngeal System Development
Branching Involved In Prostate Gland Morphogenesis
Epithelial Cell Proliferation Involved In Salivary Gland Morphogenesis
Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Cellular Response To Steroid Hormone Stimulus
Cellular Response To Hypoxia
Mitotic Cell Cycle Arrest
Negative Regulation Of Estrogen Receptor Binding
Positive Regulation Of Androgen Secretion
Positive Regulation Of Response To DNA Damage Stimulus
Positive Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
Prostate cancer
GWAS
Birth weight (
31043758
)
Mean corpuscular hemoglobin (
29403010
)
Mean corpuscular hemoglobin concentration (
29403010
)
Prostate cancer (
32986714
26443449
)
Prostate-specific antigen levels (
28139693
)
Waist-hip ratio (
25673412
)
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI (age <50) (
26426971
)
Waist-to-hip ratio adjusted for BMI (age >50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
101 interacting genes:
ARID5A
ARMCX2
ARSA
ATN1
ATXN1
BATF3
BOLL
C1orf94
CAMK2A
CCDC33
CCNK
CEACAM6
CERCAM
CHAC1
CLASRP
CLDN7
CREM
CRX
CRYBA1
DAB1
DAZAP2
DEDD2
DTX2
DVL2
EFEMP2
EWSR1
FAM166A
FAM168A
FAM168B
FBF1
HNRNPLL
HOXC13
HYPK
KHDC4
KLHDC7B
KRTAP12-2
KRTAP13-2
KRTAP13-4
KRTAP15-1
KRTAP19-5
KRTAP19-6
KRTAP19-7
KRTAP26-1
KRTAP6-1
KRTAP6-2
KRTAP7-1
LASP1
LENG8
LSM4
LZTS2
MAGED1
MDFI
MED7
MGAT5B
MSX2
MVP
NANOG
NEU4
NKX1-2
NKX3-1
PITX1
PLAC8
PLOD3
POLR3D
POU2AF1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PRR34
PSMF1
RADIL
RAMAC
RBFOX1
RBFOX2
RBM11
RBPMS
RBPMS2
RNF4
SERF2
SNAPC1
SUMO1
TENT5A
TENT5B
TENT5C
TENT5D
TEP1
TLE5
TMCC2
TOLLIP
TRIP13
UBAP2
UBE2I
UPF1
UTP6
VAC14
VENTX
VPS25
ZBTB32
ZNF683
37 interacting genes:
AEN
CCT7
CD200R1L
CENPX
CHPF
CKAP4
FEM1B
HIPK2
HMG20B
HNRNPA0
HSP90B1
LMCD1
MAN2B1
MNAT1
MT-ND4
PEBP1
PTMS
RABL6
RARG
RHOXF2
RNF4
RPL37A
RPSA
SLC22A18
SP1
SP2
SP3
SP4
SP5
SPDEF
SRF
STMN3
TEX264
TOPORS
TPT1
WDR77
ZNF417
Entrez ID
84528
4824
HPRD ID
02345
03620
Ensembl ID
ENSG00000131721
ENSG00000167034
Uniprot IDs
Q9BQY4
Q99801
PDB IDs
2L9R
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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