RAD54B and TRAPPC6A

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RAD54B	TRAPPC6A
Description		RAD54 homolog B	trafficking protein particle complex subunit 6A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Golgi Membrane Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex
	Molecular Function	DNA Binding DNA Helicase Activity RNA Helicase Activity Protein Binding ATP Binding DNA Translocase Activity	Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Mitotic Recombination Reciprocal Meiotic Recombination Determination Of Adult Lifespan Response To Ionizing Radiation DNA Duplex Unwinding Response To Drug	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity COPII Vesicle Coating Melanosome Assembly
Pathways			COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs			S-palmitoyl-L-cysteine
Diseases
GWAS		Nonsyndromic cleft lip with cleft palate ( 28232668)	Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Cerebrospinal fluid AB1-42 levels ( 28247064)
Interacting Genes		30 interacting genes: ANKRD36BP1 ATPAF2 BAAT CCDC33 CDC23 CSNK1E DMC1 DYRK2 ELOA ENKD1 GMCL1 GORASP2 IGFBP3 LNX1 MDM4 MYO15B NIF3L1 NUDT18 PRKAA1 PSMA1 RAD51 RIBC2 SFRP2 SUMO1 TCEANC TRAPPC6A TRMO UBE2I WRN ZNF580	47 interacting genes: BAG4 CAVIN2 CD2BP2 CRYAB CTDSP1 EFS EYA2 FOXN1 GGA3 GINS3 GOLGA6A GORASP2 HOXA1 HSPB8 IKZF3 INCA1 KANK4 KRTAP13-2 LHX4 MYOZ3 PAX6 PFDN5 PRR22 RAB3IP RAD54B REL RUSC1 SCOC SERTAD3 SF3B5 SMUG1 TAX1BP1 TEPSIN TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B TRIM35 TTC23 UBAP2 YPEL3 ZFP90 ZMIZ2 ZNRD2
Entrez ID		25788	79090
HPRD ID		05049	14503
Ensembl ID		ENSG00000197275	ENSG00000007255
Uniprot IDs		O95073 Q9Y620	B7TZ90 O75865
PDB IDs			2C0J 2J3T
Enriched GO Terms of Interacting Partners?
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