KCTD13 and ZMYND19

Data Source:
HPRD (two hybrid)

		KCTD13	ZMYND19
Description		potassium channel tetramerization domain containing 13	zinc finger MYND-type containing 19
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nuclear Body Cul3-RING Ubiquitin Ligase Complex	Cytoplasm Plasma Membrane Synapse
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Protein Domain Specific Binding Small GTPase Binding Identical Protein Binding	Protein Binding Metal Ion Binding
	Biological Process	Cell Migration Protein Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Stress Fiber Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Replication Positive Regulation Of Synaptic Transmission Protein Homooligomerization Neural Precursor Cell Proliferation
Pathways
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Hand grip strength ( 29691431) Menarche (age at onset) ( 25231870) Schizophrenia ( 28991256 25056061 29483656 30285260) Urinary sodium excretion ( 31409800)	Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Systolic blood pressure ( 30578418)
Interacting Genes		21 interacting genes: ADRB2 ARMC7 CDC37 CRK CUL3 EXOSC5 GORASP2 KAT7 KCTD10 LNX1 NTAQ1 NUDT18 PCNA POLD2 POLR1C PPARG PSMA1 RHOA TNFAIP1 VTA1 ZMYND19	52 interacting genes: ANKRD55 C19orf54 CBWD1 CBWD3 CBWD5 CCNI CEACAM6 CPSF6 DTX3 ENOX1 FIP1L1 FNDC3B GAPDHS GGN GMEB2 GORASP2 GRB10 GSE1 GTF2F2 HACL1 HOMEZ INCA1 KCTD13 KCTD21 LZTS1 LZTS2 MCHR1 MLLT6 NAB2 PNMA5 PPP1R37 PRKAB2 PRKAR1B PRMT5 PSMA1 PTGES3L-AARSD1 RFX6 SAXO1 SCN5A SELENOV SS18L1 TBRG1 TNFAIP1 TNNT1 TOLLIP TOX4 TRIM27 TRIM45 TUBB WDR77 ZBTB2 ZXDC
Entrez ID		253980	116225
HPRD ID		12339	15743
Ensembl ID		ENSG00000174943	ENSG00000165724
Uniprot IDs		A0A3B3IS45 Q8WZ19	Q96E35
PDB IDs		4UIJ
Enriched GO Terms of Interacting Partners?
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