KCTD13 and KCTD10

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		KCTD13	KCTD10
Description		potassium channel tetramerization domain containing 13	potassium channel tetramerization domain containing 10
Image
GO Annotations	Cellular Component	Nucleoplasm Nuclear Body Cul3-RING Ubiquitin Ligase Complex	Nucleoplasm Cytosol Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Protein Domain Specific Binding Small GTPase Binding Identical Protein Binding	Ubiquitin-protein Transferase Activity Notch Binding Protein Binding Identical Protein Binding
	Biological Process	Cell Migration Protein Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Stress Fiber Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Replication Positive Regulation Of Synaptic Transmission Protein Homooligomerization Neural Precursor Cell Proliferation	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Hand grip strength ( 29691431) Menarche (age at onset) ( 25231870) Schizophrenia ( 28991256 25056061 29483656 30285260) Urinary sodium excretion ( 31409800)	Coronary artery disease ( 33020668) Fish- and plant-related diet ( 32066663) HDL cholesterol ( 20864672) Non-oily fish consumption ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663)
Interacting Genes		21 interacting genes: ADRB2 ARMC7 CDC37 CRK CUL3 EXOSC5 GORASP2 KAT7 KCTD10 LNX1 NTAQ1 NUDT18 PCNA POLD2 POLR1C PPARG PSMA1 RHOA TNFAIP1 VTA1 ZMYND19	8 interacting genes: CUL3 DVL3 ITSN2 KCTD13 NTAQ1 TCEA2 TEX11 TNFAIP1
Entrez ID		253980	83892
HPRD ID		12339	13762
Ensembl ID		ENSG00000174943	ENSG00000110906
Uniprot IDs		A0A3B3IS45 Q8WZ19	A0A024RBJ2 Q9H3F6
PDB IDs		4UIJ	5FTA
Enriched GO Terms of Interacting Partners?
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