MMS22L and ESCO2

Data Source:
BioGRID (affinity chromatography technology, pull down)

		MMS22L	ESCO2
Description		MMS22 like, DNA repair protein	establishment of sister chromatid cohesion N-acetyltransferase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol FACT Complex MCM Complex Nuclear Replication Fork	Chromatin XY Body Nucleoplasm Chromosome Pericentric Heterochromatin Golgi Apparatus Chromocenter Cell Junction Site Of Double-strand Break
	Molecular Function	Protein Binding	Lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Protein Binding Acetyltransferase Activity Metal Ion Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Replication Fork Processing	Hematopoietic Progenitor Cell Differentiation Regulation Of DNA Replication Double-strand Break Repair Sister Chromatid Cohesion Post-translational Protein Acetylation Protein Localization To Chromatin
Pathways			Establishment of Sister Chromatid Cohesion
Drugs
Diseases			ESCO2-related disorders, including: Roberts syndrome; SC phocomelia syndrome
GWAS		Adult body size ( 32376654) Automobile speeding propensity ( 30643258) Body mass index ( 25673413 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Chronotype ( 30696823) Gut microbiota (bacterial taxa) ( 27694959) Hand grip strength ( 29691431) Morning person ( 30696823) Multiple sclerosis (OCB status) ( 23785401) Number of sexual partners ( 30643258) Photic sneeze reflex ( 27182965) Post bronchodilator FEV1 in COPD ( 26634245) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes		4 interacting genes: ESCO2 FBXW7 RAD51 RPA1	12 interacting genes: FXR1 GOLGA2 MCM2 MCM4 MCM5 MCM6 MCM7 MMS22L PCNA PICK1 RABEP1 SMC3
Entrez ID		253714	157570
HPRD ID		12865	18564
Ensembl ID		ENSG00000146263	ENSG00000171320
Uniprot IDs		Q6ZRQ5	Q56NI9
PDB IDs
Enriched GO Terms of Interacting Partners?
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