PRPF6 and TIMM44

Data Source:
BioGRID (two hybrid)

		PRPF6	TIMM44
Description		pre-mRNA processing factor 6	translocase of inner mitochondrial membrane 44
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Fibrillar Center Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	Transcription Coactivator Activity RNA Binding Protein Binding Ribonucleoprotein Complex Binding Androgen Receptor Binding	Protein Binding ATP Binding Chaperone Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Localization RNA Splicing Positive Regulation Of Transcription By RNA Polymerase II	Protein Targeting To Mitochondrion Protein Import Into Mitochondrial Matrix
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	Mitochondrial protein import
Drugs
Diseases
GWAS		Body mass index ( 28552196) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Prostate cancer ( 23535732) Refractive error ( 32231278)
Interacting Genes		12 interacting genes: AR ARAF CD2BP2 ESR1 NR3C1 RAF1 SMARCA2 SRRM2 SUMO2 TIMM44 TXNL4B YWHAB	8 interacting genes: ARAF CCDC57 CMTM5 HSPA9 PRPF6 SFT2D2 TIMM17A UBASH3A
Entrez ID		24148	10469
HPRD ID		10729	05450
Ensembl ID		ENSG00000101161	ENSG00000104980
Uniprot IDs		O94906	O43615
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9	2CW9
Enriched GO Terms of Interacting Partners?
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