TIMM44 and HSPA9

Data Source:
BioGRID (pull down)

		TIMM44	HSPA9
Description		translocase of inner mitochondrial membrane 44	heat shock protein family A (Hsp70) member 9
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GO Annotations	Cellular Component	Fibrillar Center Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix	SAM Complex Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Focal Adhesion Mitochondrial Nucleoid Extracellular Exosome MIB Complex
	Molecular Function	Protein Binding ATP Binding Chaperone Binding	RNA Binding Protein Binding ATP Binding ATPase Activity Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Protein Folding Chaperone Unfolded Protein Binding Misfolded Protein Binding
	Biological Process	Protein Targeting To Mitochondrion Protein Import Into Mitochondrial Matrix	Protein Export From Nucleus Inner Mitochondrial Membrane Organization Iron-sulfur Cluster Assembly Erythrocyte Differentiation Cellular Response To Unfolded Protein Interleukin-12-mediated Signaling Pathway Protein Refolding Negative Regulation Of Apoptotic Process Regulation Of Erythrocyte Differentiation Negative Regulation Of Erythrocyte Differentiation Chaperone Cofactor-dependent Protein Refolding Negative Regulation Of Hematopoietic Stem Cell Differentiation Negative Regulation Of Hemopoiesis
Pathways		Mitochondrial protein import	Mitochondrial protein import Regulation of HSF1-mediated heat shock response Cristae formation Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) Schizophrenia ( 25056061 29483656)
Interacting Genes		8 interacting genes: ARAF CCDC57 CMTM5 HSPA9 PRPF6 SFT2D2 TIMM17A UBASH3A	26 interacting genes: APP DNAJC19 DNLZ ERBB2 ERCC6 FGF1 HSP90B1 HSPBP1 LAMTOR5 LINC01554 LSM8 MATK MVD NELFB PTPN11 PTPRF SIRPA STUB1 SUMO2 SUMO4 SUPT6H TIMM44 TP53 XPO1 YKT6 YWHAG
Entrez ID		10469	3313
HPRD ID		05450	02770
Ensembl ID		ENSG00000104980	ENSG00000113013
Uniprot IDs		O43615	A0A384P5G6 P38646
PDB IDs		2CW9	3N8E 4KBO 6NHK 6P2U 6PMT
Enriched GO Terms of Interacting Partners?
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