PRPF6 and TXNL4B

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		PRPF6	TXNL4B
Description		pre-mRNA processing factor 6	thioredoxin like 4B
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nucleoplasm Spliceosomal Complex U5 SnRNP Cytosol U4/U6 X U5 Tri-snRNP Complex
	Molecular Function	Transcription Coactivator Activity RNA Binding Protein Binding Ribonucleoprotein Complex Binding Androgen Receptor Binding	Protein Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Localization RNA Splicing Positive Regulation Of Transcription By RNA Polymerase II	MRNA Splicing, Via Spliceosome Cell Cycle
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Body mass index ( 28552196) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Prostate cancer ( 23535732) Refractive error ( 32231278)	Apolipoprotein B levels ( 32203549) Blood protein levels ( 29875488 28240269) Coronary artery disease ( 29212778) Hematocrit ( 32888494) Hemoglobin ( 32888494) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 30718733 32154731) Medication use (HMG CoA reductase inhibitors) ( 31015401) Red blood cell count ( 32888494) Total cholesterol levels ( 30718733) Triglyceride levels ( 32203549 32154731)
Interacting Genes		12 interacting genes: AR ARAF CD2BP2 ESR1 NR3C1 RAF1 SMARCA2 SRRM2 SUMO2 TIMM44 TXNL4B YWHAB	14 interacting genes: AIPL1 ALKBH4 BHLHE40 CENATAC MEOX1 MEOX2 PICK1 PLEKHF2 PNMA5 PRPF6 REL SF1 SPG21 TCF4
Entrez ID		24148	54957
HPRD ID		10729	11655
Ensembl ID		ENSG00000101161	ENSG00000140830
Uniprot IDs		O94906	Q9NX01
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9	1XBS 3GIX 4IN0
Enriched GO Terms of Interacting Partners?
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