TIMM44 and PRPF6

Data Source:
BioGRID (two hybrid)

		TIMM44	PRPF6
Description		translocase of inner mitochondrial membrane 44	pre-mRNA processing factor 6
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GO Annotations	Cellular Component	Fibrillar Center Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding ATP Binding Chaperone Binding	Transcription Coactivator Activity RNA Binding Protein Binding Ribonucleoprotein Complex Binding Androgen Receptor Binding
	Biological Process	Protein Targeting To Mitochondrion Protein Import Into Mitochondrial Matrix	Spliceosomal Tri-snRNP Complex Assembly Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Localization RNA Splicing Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Mitochondrial protein import	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS			Body mass index ( 28552196) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Prostate cancer ( 23535732) Refractive error ( 32231278)
Interacting Genes		8 interacting genes: ARAF CCDC57 CMTM5 HSPA9 PRPF6 SFT2D2 TIMM17A UBASH3A	12 interacting genes: AR ARAF CD2BP2 ESR1 NR3C1 RAF1 SMARCA2 SRRM2 SUMO2 TIMM44 TXNL4B YWHAB
Entrez ID		10469	24148
HPRD ID		05450	10729
Ensembl ID		ENSG00000104980	ENSG00000101161
Uniprot IDs		O43615	O94906
PDB IDs		2CW9	3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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