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MLX
Description
MAX dimerization protein MLX
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Nuclear Membrane
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
ChREBP activates metabolic gene expression
ChREBP activates metabolic gene expression
Drugs
Diseases
GWAS
Crohn's disease (
21102463
)
Type 2 diabetes (
30297969
29632382
30718926
)
Type 2 diabetes (time to event) (
32589924
)
Interacting Genes
31 interacting genes:
APP
BACH2
BEND7
CASK
CCT6A
DDIT4L
GABARAPL1
GABARAPL2
ID3
KRTAP13-3
LNX1
LNX2
MAD1L1
MEI4
MEOX1
MEOX2
MLXIP
MLXIPL
MNT
MXD1
MXD4
PIAS2
RBM39
RHBDD2
SAP30BP
TEPSIN
TLE5
TNNT2
UBE2I
ZBTB32
ZNF620
Entrez ID
6945
HPRD ID
04278
Ensembl ID
ENSG00000108788
Uniprot IDs
Q9UH92
PDB IDs
Enriched GO Terms of Interacting Partners
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