FOLR3 and RNF115

Data Source:
BioGRID (two hybrid)

		FOLR3	RNF115
Description		folate receptor gamma	ring finger protein 115
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Membrane Extrinsic Component Of Membrane Anchored Component Of External Side Of Plasma Membrane Specific Granule Lumen Tertiary Granule Lumen	Cytosol
	Molecular Function	Protein Binding Folic Acid Binding Signaling Receptor Activity	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cell Adhesion Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Folic Acid Transport Sperm-egg Recognition Neutrophil Degranulation	Protein Polyubiquitination Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination
Pathways		Neutrophil degranulation	Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Folic acid Vintafolide
Diseases
GWAS		Blood protein levels ( 29875488)	Apolipoprotein A1 levels ( 32203549) Breast cancer ( 25751625 29059683) HDL cholesterol levels ( 32203549) Platelet distribution width ( 32888494)
Interacting Genes		3 interacting genes: ANKRD11 RNF115 UBQLN1	32 interacting genes: AKT1 APP ATN1 CDK10 CST3 DAZAP2 DOCK4 EGFR FOLR3 HRAS IGHA1 MDM4 MFAP4 NFKBIA RAB7A RAD23A RPL18A TTR UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2I UBE2N UBE2W USP9X VCP ZNRD2
Entrez ID		2352	27246
HPRD ID		03918	18328
Ensembl ID		ENSG00000110203	ENSG00000265491
Uniprot IDs		P41439	Q9Y4L5
PDB IDs
Enriched GO Terms of Interacting Partners?
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