POLR1H and GPR20

Data Source:
BioGRID (two hybrid)

		POLR1H	GPR20
Description		RNA polymerase I subunit H	G protein-coupled receptor 20
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase I Complex	Cytosol Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex
	Molecular Function	Nucleic Acid Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Zinc Ion Binding	G Protein-coupled Receptor Activity
	Biological Process	Nucleobase-containing Compound Metabolic Process Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription MRNA Cleavage Positive Regulation Of Gene Expression, Epigenetic	G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972) Birth weight ( 31043758) Blood pressure traits (multi-trait analysis) ( 28498854) Diastolic blood pressure ( 27841878 27618447 28498854) Discordance in emotional problems in monozygotic twins ( 27043157) Height ( 31562340) Response to fenofibrate (total cholesterol levels) ( 27002377) Systolic blood pressure ( 27841878 27618447 28498854 31217584)
Interacting Genes		18 interacting genes: APOA1 ATXN2 CIC DUSP1 FHL3 GFI1B GPR20 HAX1 IL15 IVNS1ABP MAPK8IP2 NONO SACS SERPINA3 TNS2 TRIML2 UBE2I ZNF593	3 interacting genes: JAM2 POLR1H RPL31
Entrez ID		30834	2843
HPRD ID		09601	03550
Ensembl ID		ENSG00000066379	ENSG00000204882
Uniprot IDs		Q2L6J2 Q9P1U0	Q59GP3 Q99678
PDB IDs
Enriched GO Terms of Interacting Partners?
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