NACAD and MAP4K2

		NACAD	MAP4K2
Description		NAC alpha domain containing	mitogen-activated protein kinase kinase kinase kinase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Nascent Polypeptide-associated Complex	Golgi Membrane Basolateral Plasma Membrane
	Molecular Function	Protein Binding Unfolded Protein Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding MAP Kinase Kinase Kinase Kinase Activity Mitogen-activated Protein Kinase Kinase Kinase Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Protein Targeting To Membrane	Activation Of MAPKKK Activity Protein Phosphorylation Vesicle Targeting Immune Response JNK Cascade Activation Of JUN Kinase Activity Intracellular Signal Transduction Innate Immune Response Positive Regulation Of JNK Cascade
Pathways
Drugs			Fostamatinib
Diseases
GWAS		Eosinophil counts ( 32888494)	Serum uric acid levels ( 32514006) Urate levels ( 21768215)
Interacting Genes		10 interacting genes: AGTR1 CBLC HDAC6 MAP4K2 NR4A1 PTK2 RPS27 STAT3 TNNT1 YAE1	13 interacting genes: DEFB1 HNRNPA2B1 MAP2K4 MAP3K11 MCM3AP-AS1 NACAD POT1 PRDX4 RAB8A SERPINA4 SNRNP35 TRAF2 XRCC6
Entrez ID		23148	5871
HPRD ID			04408
Ensembl ID		ENSG00000136274	ENSG00000168067
Uniprot IDs		O15069	A0A024R567 Q12851
PDB IDs
Enriched GO Terms of Interacting Partners?
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