MAP4K2

Description		mitogen-activated protein kinase kinase kinase kinase 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Basolateral Plasma Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding MAP Kinase Kinase Kinase Kinase Activity Mitogen-activated Protein Kinase Kinase Kinase Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Activation Of MAPKKK Activity Protein Phosphorylation Vesicle Targeting Immune Response JNK Cascade Activation Of JUN Kinase Activity Intracellular Signal Transduction Innate Immune Response Positive Regulation Of JNK Cascade
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Serum uric acid levels ( 32514006) Urate levels ( 21768215)
Novel Interacting Genes		1 novel interacting genes: RELA
Interacting Genes		13 interacting genes: DEFB1 HNRNPA2B1 MAP2K4 MAP3K11 MCM3AP-AS1 NACAD POT1 PRDX4 RAB8A SERPINA4 SNRNP35 TRAF2 XRCC6
Entrez ID		5871
HPRD ID		04408
Ensembl ID		ENSG00000168067
Uniprot IDs		A0A024R567 Q12851
PDB IDs
Enriched GO Terms of Interacting Partners?
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