SARM1 and CCDC47

Data Source:
BioGRID (affinity chromatography technology, pull down)

		SARM1	CCDC47
Description		sterile alpha and TIR motif containing 1	coiled-coil domain containing 47
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Microtubule Axon Dendrite Extrinsic Component Of Mitochondrial Outer Membrane Synapse	Endoplasmic Reticulum Membrane Integral Component Of Membrane Rough Endoplasmic Reticulum Membrane
	Molecular Function	NAD+ Nucleosidase Activity Protein Binding Signaling Adaptor Activity NAD(P)+ Nucleosidase Activity NAD+ Nucleotidase, Cyclic ADP-ribose Generating	RNA Binding Calcium Ion Binding Protein Binding
	Biological Process	Signal Transduction Nervous System Development Response To Glucose NAD Catabolic Process Cell Differentiation Negative Regulation Of MyD88-independent Toll-like Receptor Signaling Pathway Regulation Of Apoptotic Process Innate Immune Response Response To Axon Injury Regulation Of Dendrite Morphogenesis Regulation Of Neuron Death Positive Regulation Of Neuron Death	Osteoblast Differentiation ER Overload Response Endoplasmic Reticulum Organization Post-embryonic Development Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Calcium Ion Homeostasis ERAD Pathway
Pathways
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 27455348) Amyotrophic lateral sclerosis (sporadic) ( 28931804) Blood protein levels ( 29875488 28240269) Osteoprotegerin levels ( 25080503)
Interacting Genes		6 interacting genes: CCDC47 IRAK2 MYD88 NLRX1 STT3A TICAM2	8 interacting genes: IRAK1 IRF7 PTEN RPL7A SARM1 STING1 TIRAP TOM1L1
Entrez ID		23098	57003
HPRD ID		09664	17041
Ensembl ID		ENSG00000004139	ENSG00000108588
Uniprot IDs		Q05B42 Q0D2N8 Q6SZW1	Q96A33
PDB IDs		6O0Q 6O0R 6O0S 6O0T 6O0U 6O0V 6O1B 6QWV 6WPK 7CM5 7CM6 7CM7	6W6L
Enriched GO Terms of Interacting Partners?
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