SARM1 and STT3A

Data Source:
BioGRID (pull down)

		SARM1	STT3A
Description		sterile alpha and TIR motif containing 1	STT3 oligosaccharyltransferase complex catalytic subunit A
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Microtubule Axon Dendrite Extrinsic Component Of Mitochondrial Outer Membrane Synapse	Endoplasmic Reticulum Membrane Oligosaccharyltransferase Complex Membrane Integral Component Of Membrane Oligosaccharyltransferase III Complex
	Molecular Function	NAD+ Nucleosidase Activity Protein Binding Signaling Adaptor Activity NAD(P)+ Nucleosidase Activity NAD+ Nucleotidase, Cyclic ADP-ribose Generating	Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding Metal Ion Binding
	Biological Process	Signal Transduction Nervous System Development Response To Glucose NAD Catabolic Process Cell Differentiation Negative Regulation Of MyD88-independent Toll-like Receptor Signaling Pathway Regulation Of Apoptotic Process Innate Immune Response Response To Axon Injury Regulation Of Dendrite Morphogenesis Regulation Of Neuron Death Positive Regulation Of Neuron Death	Protein N-linked Glycosylation Protein N-linked Glycosylation Via Asparagine Co-translational Protein Modification Post-translational Protein Modification
Pathways			Asparagine N-linked glycosylation Maturation of spike protein
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 27455348) Amyotrophic lateral sclerosis (sporadic) ( 28931804) Blood protein levels ( 29875488 28240269) Osteoprotegerin levels ( 25080503)	Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Breast cancer (survival) ( 25890600) Schizophrenia ( 21926974)
Interacting Genes		6 interacting genes: CCDC47 IRAK2 MYD88 NLRX1 STT3A TICAM2	6 interacting genes: CSDE1 HJURP IRAK2 ITM2C SARM1 STING1
Entrez ID		23098	3703
HPRD ID		09664	03086
Ensembl ID		ENSG00000004139	ENSG00000134910
Uniprot IDs		Q05B42 Q0D2N8 Q6SZW1	P46977
PDB IDs		6O0Q 6O0R 6O0S 6O0T 6O0U 6O0V 6O1B 6QWV 6WPK 7CM5 7CM6 7CM7	6S7O
Enriched GO Terms of Interacting Partners?
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