CCDC47 and TOM1L1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CCDC47	TOM1L1
Description		coiled-coil domain containing 47	target of myb1 like 1 membrane trafficking protein
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GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Rough Endoplasmic Reticulum Membrane	Cytoplasm Lysosome Endosome Golgi Stack Cytosol Endosome Membrane Membrane Extracellular Exosome
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding	Protein Binding SH3 Domain Binding Protein Kinase Binding Clathrin Binding Protein Kinase Activator Activity Ubiquitin Binding
	Biological Process	Osteoblast Differentiation ER Overload Response Endoplasmic Reticulum Organization Post-embryonic Development Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Calcium Ion Homeostasis ERAD Pathway	Intracellular Protein Transport Signal Transduction Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Mitotic Nuclear Division Regulation Of DNA Biosynthetic Process
Pathways
Drugs
Diseases
GWAS			Carotid intima media thickness x smoking interaction ( 32117412) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965) Urinary albumin-to-creatinine ratio ( 32600054)
Interacting Genes		8 interacting genes: IRAK1 IRF7 PTEN RPL7A SARM1 STING1 TIRAP TOM1L1	29 interacting genes: AMFR CCDC47 CELF1 COPS7A CWF19L1 DNAJB13 FYN GLUD2 GRB2 GSN HGS HNRNPH1 MAP3K3 NDC80 NOMO1 PDPN PELP1 PHYH PIK3R1 PWP2 RAB18 TASOR TOLLIP TSG101 TUBA1B UBC UBXN4 VAV2 VCP
Entrez ID		57003	10040
HPRD ID		17041	05266
Ensembl ID		ENSG00000108588	ENSG00000141198
Uniprot IDs		Q96A33	O75674 Q8NI65
PDB IDs		6W6L	3RRU
Enriched GO Terms of Interacting Partners?
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