STT3A and ITM2C

Data Source:
HPRD (two hybrid)

		STT3A	ITM2C
Description		STT3 oligosaccharyltransferase complex catalytic subunit A	integral membrane protein 2C
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Oligosaccharyltransferase Complex Membrane Integral Component Of Membrane Oligosaccharyltransferase III Complex	Lysosome Lysosomal Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding Metal Ion Binding	Amyloid-beta Binding Protein Binding ATP Binding
	Biological Process	Protein N-linked Glycosylation Protein N-linked Glycosylation Via Asparagine Co-translational Protein Modification Post-translational Protein Modification	Negative Regulation Of Neuron Projection Development Neuron Differentiation Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Asparagine N-linked glycosylation Maturation of spike protein
Drugs
Diseases
GWAS		Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Breast cancer (survival) ( 25890600) Schizophrenia ( 21926974)	Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		6 interacting genes: CSDE1 HJURP IRAK2 ITM2C SARM1 STING1	11 interacting genes: BACE1 CCL4L2 CXCL9 FNDC9 FURIN MTNR1B OLFM4 RNF7 SLC22A2 STT3A UPK2
Entrez ID		3703	81618
HPRD ID		03086	17167
Ensembl ID		ENSG00000134910	ENSG00000135916
Uniprot IDs		P46977	B8ZZM6 Q9NQX7
PDB IDs		6S7O
Enriched GO Terms of Interacting Partners?
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