CDK19 and USP54

Data Source:
BioGRID (affinity chromatography technology)

		CDK19	USP54
Description		cyclin dependent kinase 19	ubiquitin specific peptidase 54
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Mediator Complex
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Activity ATP Binding RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding
	Biological Process	Protein Phosphorylation Positive Regulation Of Apoptotic Process Positive Regulation Of Inflammatory Response Regulation Of Cell Cycle Cellular Response To Lipopolysaccharide	Protein Deubiquitination Protein Phosphopantetheinylation
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		General risk tolerance (MTAG) ( 30643258) Zinc levels ( 26025379)	Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		7 interacting genes: BCL6 EIF3F PRMT5 SMARCA4 SRSF7 SUZ12 WDR77	88 interacting genes: ANKRD11 ANKS1A ARMC7 ATN1 ATXN1 ATXN1L ATXN7L2 BFSP2 BHLHE40 CARD10 CCDC13 CCDC24 CCNK CDC23 CHCHD2 CHERP CHMP1B CHMP2A CHMP2B CHMP4C CSTF2 CYSRT1 DMRT3 DOK6 DTX2 EIF4E2 EPM2AIP1 EXOC8 FAM124B FBXO17 FNDC3B FOXI1 GCM2 HGS HNF1B HNRNPF HOXC8 IGFN1 INSC KCTD9 LMO3 LNX1 MED25 MID2 NUDT22 NXT2 OIP5 OTX1 PCSK5 PHF1 PLA2G6 PLAC8 PLEKHN1 POLR1C PRDM6 PRKAB2 PRR35 QRICH1 RACK1 RAMAC RBPMS2 RHOBTB3 RNF208 SEC24A SHARPIN SHC3 SMARCD1 SMYD1 SNRPB SS18L1 STK16 TBX6 TCEA2 TEKT5 TENT5B TFAP2D TLE5 TNS2 TOLLIP TSEN15 TSSK3 TTC19 UBC USP2 VENTX ZCCHC14 ZNF148 ZNF76
Entrez ID		23097	159195
HPRD ID		07627	15641
Ensembl ID		ENSG00000155111	ENSG00000166348
Uniprot IDs		B4DUB1 I6W807 Q9BWU1	B7Z7X1 Q70EL1
PDB IDs
Enriched GO Terms of Interacting Partners?
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