ELL2 and EAF1

Data Source:
HPRD (in vivo)

		ELL2	EAF1
Description		elongation factor for RNA polymerase II 2	ELL associated factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Elongation Factor Complex	Nucleoplasm Transcription Elongation Factor Complex Cajal Body Nuclear Body Nuclear Speck Super Elongation Complex Intracellular Membrane-bounded Organelle Intercellular Bridge
	Molecular Function	Protein Binding	Transcription Elongation Regulator Activity Protein Binding
	Biological Process	Transcription Elongation From RNA Polymerase II Promoter SnRNA Transcription By RNA Polymerase II	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Body mass index ( 26426971) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) IgA levels ( 28628107) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Mean corpuscular hemoglobin ( 32888494) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Non-albumin protein levels ( 29403010) Serum total protein level ( 23022100) Telomere length ( 30185882)
Interacting Genes		7 interacting genes: AFF4 AQP2 CASK EAF1 EXOC8 PRKAB2 SIAH1	53 interacting genes: AP2M1 APP ARID4B BEND7 BHLHB9 CCDC150 CCDC33 CEP70 CEP76 DNTTIP1 DPPA4 ELL ELL2 ELL3 FAM228A GADD45GIP1 GAS8 GCSAML GOLGA6L9 GRHL3 GTF2H1 GTF2H4 HOMER3 HSF2BP KEAP1 KIAA1328 MAB21L3 MIPOL1 NUMB PAX6 PICK1 PIH1D1 PSME3 RYBP SDCBP SEMG1 SH3RF1 SRP14 STAC3 TCEA2 TFCP2 TFPT TLE5 TNFAIP8 TNNI1 TRAF2 TRIM62 VAX1 YAF2 ZBTB14 ZNF143 ZNF202 ZNF620
Entrez ID		22936	85403
HPRD ID		11798	12209
Ensembl ID		ENSG00000118985	ENSG00000144597
Uniprot IDs		O00472 Q59FW6 Q7Z656	Q96JC9
PDB IDs		2E5N 5JW9
Enriched GO Terms of Interacting Partners?
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