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EAF1 and NUMB
Data Source:
BioGRID
(two hybrid)
EAF1
NUMB
Description
ELL associated factor 1
NUMB endocytic adaptor protein
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Transcription Elongation Factor Complex
Cajal Body
Nuclear Body
Nuclear Speck
Super Elongation Complex
Intracellular Membrane-bounded Organelle
Intercellular Bridge
Nucleus
Cytoplasm
Early Endosome
Plasma Membrane
Clathrin-coated Pit
Focal Adhesion
Endosome Membrane
Basolateral Plasma Membrane
Extrinsic Component Of Plasma Membrane
Clathrin-coated Vesicle
Apical Part Of Cell
Glutamatergic Synapse
Molecular Function
Transcription Elongation Regulator Activity
Protein Binding
Protein Binding
Beta-catenin Binding
Alpha-catenin Binding
Cadherin Binding
Biological Process
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Axonogenesis
Lateral Ventricle Development
Neuroblast Division In Subventricular Zone
Positive Regulation Of Cell Migration
Adherens Junction Organization
Positive Regulation Of Neurogenesis
Regulation Of Postsynaptic Neurotransmitter Receptor Internalization
Negative Regulation Of Protein Localization To Plasma Membrane
Pathways
Formation of RNA Pol II elongation complex
RNA Polymerase II Pre-transcription Events
RNA Polymerase II Transcription Elongation
Activated NOTCH1 Transmits Signal to the Nucleus
Recycling pathway of L1
Degradation of GLI1 by the proteasome
Hedgehog 'on' state
Drugs
Diseases
GWAS
Bipolar disorder with mood-incongruent psychosis (
23092984
)
Coronary artery calcification (
17903303
)
Hemoglobin (
32888494
)
Macular thickness (
30535121
)
Multisite chronic pain (
31194737
)
Interacting Genes
53 interacting genes:
AP2M1
APP
ARID4B
BEND7
BHLHB9
CCDC150
CCDC33
CEP70
CEP76
DNTTIP1
DPPA4
ELL
ELL2
ELL3
FAM228A
GADD45GIP1
GAS8
GCSAML
GOLGA6L9
GRHL3
GTF2H1
GTF2H4
HOMER3
HSF2BP
KEAP1
KIAA1328
MAB21L3
MIPOL1
NUMB
PAX6
PICK1
PIH1D1
PSME3
RYBP
SDCBP
SEMG1
SH3RF1
SRP14
STAC3
TCEA2
TFCP2
TFPT
TLE5
TNFAIP8
TNNI1
TRAF2
TRIM62
VAX1
YAF2
ZBTB14
ZNF143
ZNF202
ZNF620
37 interacting genes:
AP2A1
AP2A2
APP
DNAJC5
DPYSL2
EAF1
EGFR
EPS15
FBXO7
FRS3
IRS1
ITCH
ITGB2
ITGB3
ITGB5
L1CAM
LNX1
LNX2
MAPK8IP2
MDM2
NEDD4
NOTCH1
OLIG1
PALS1
PDZK1IP1
PRKCA
PRKCB
PRKCD
PRKCE
PRKCG
PRKCH
PRKCZ
PTEN
RPL3
SIAH1
SPANXN2
TERF2
Entrez ID
85403
8650
HPRD ID
12209
04767
Ensembl ID
ENSG00000144597
ENSG00000133961
Uniprot IDs
Q96JC9
A0A024R681
A0A024R684
A0A024R6C4
A0A024R6F4
P49757
PDB IDs
5NJJ
5NJK
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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