RAB18 and CHM

Data Source:
HPRD (two hybrid)

		RAB18	CHM
Description		RAB18, member RAS oncogene family	CHM Rab escort protein
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Cytosol Plasma Membrane Endomembrane System Apical Plasma Membrane Secretory Granule Membrane Endoplasmic Reticulum Tubular Network	Nucleus Cytoplasm Cytosol Rab-protein Geranylgeranyltransferase Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Rab Geranylgeranyltransferase Activity GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Eye Development Intracellular Protein Transport Small GTPase Mediated Signal Transduction Brain Development Viral Process Lipid Droplet Organization Neutrophil Degranulation Endoplasmic Reticulum Tubular Network Organization	Protein Targeting To Membrane Small GTPase Mediated Signal Transduction Visual Perception Vesicle-mediated Transport Protein Phosphopantetheinylation Protein Geranylgeranylation Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Post-translational Protein Modification
Pathways		Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases		Warburg micro syndrome	Choroideremia (CHM); Tapetochoroidal dystrophy
GWAS		Benign childhood epilepsy with centro-temporal spikes ( 32580138) Childhood ear infection ( 27182965 28928442) Diisocyanate-induced asthma ( 25918132) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) Hip circumference adjusted for BMI ( 28552196) Refractive error ( 32231278)	Metabolite levels ( 23823483) Pit-and-Fissure caries ( 24556642) Smooth-surface caries ( 24556642)
Interacting Genes		10 interacting genes: AQP6 CHM ELOVL4 ERRFI1 FAM107A PDE6D PPP2R1A PPP2R1B TAX1BP1 TOM1L1	11 interacting genes: RAB14 RAB18 RAB1B RAB32 RAB3A RAB3B RAB3D RAB4A RAB5B RAB6A RAB7A
Entrez ID		22931	1121
HPRD ID		03731	02312
Ensembl ID		ENSG00000099246	ENSG00000188419
Uniprot IDs		A0A087X163 B7Z4P9 B7Z5V3 Q9NP72	A8K545 B4DRL9 P24386
PDB IDs		1X3S
Enriched GO Terms of Interacting Partners?
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