CHM and RAB1B

Data Source:
HPRD (in vivo)

		CHM	RAB1B
Description		CHM Rab escort protein	RAB1B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Rab-protein Geranylgeranyltransferase Complex	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Phagophore Assembly Site Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Rab Geranylgeranyltransferase Activity GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Small GTPase Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Protein Targeting To Membrane Small GTPase Mediated Signal Transduction Visual Perception Vesicle-mediated Transport Protein Phosphopantetheinylation Protein Geranylgeranylation Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Post-translational Protein Modification	Autophagosome Assembly Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Virion Assembly Post-translational Protein Modification COPII Vesicle Coating Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process Regulation Of Autophagosome Assembly
Pathways		TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases		Choroideremia (CHM); Tapetochoroidal dystrophy
GWAS		Metabolite levels ( 23823483) Pit-and-Fissure caries ( 24556642) Smooth-surface caries ( 24556642)	Bipolar disorder ( 21926972 31043756)
Interacting Genes		11 interacting genes: RAB14 RAB18 RAB1B RAB32 RAB3A RAB3B RAB3D RAB4A RAB5B RAB6A RAB7A	11 interacting genes: APP CHM GDI1 GOLGA2 MICAL1 MICAL3 MICALCL RABIF RUSC2 SMARCC2 TOMM40L
Entrez ID		1121	81876
HPRD ID		02312	11469
Ensembl ID		ENSG00000188419	ENSG00000174903
Uniprot IDs		A8K545 B4DRL9 P24386	Q9H0U4
PDB IDs			3JZA 3NKV 4HLQ 4I1O 5O74 5SZH 5SZK 6SKU
Enriched GO Terms of Interacting Partners?
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