FSD2 and ESD

Data Source:
BioGRID (two hybrid, two hybrid)

		FSD2	ESD
Description		fibronectin type III and SPRY domain containing 2	esterase D
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Sarcoplasmic Reticulum Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Lumen Cytosol Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Hydrolase Activity, Acting On Ester Bonds S-formylglutathione Hydrolase Activity Identical Protein Binding Methylumbelliferyl-acetate Deacetylase Activity Carboxylic Ester Hydrolase Activity
	Biological Process		Biological_process Formaldehyde Catabolic Process Glutathione Derivative Biosynthetic Process
Pathways			Glutathione conjugation
Drugs			Glutathione
Diseases
GWAS		HDL cholesterol levels ( 32203549) Tourette syndrome ( 30818990)	Blood protein levels ( 30072576 29875488 28240269) Metabolite levels ( 23823483)
Interacting Genes		94 interacting genes: AQP1 ARFIP2 ATF7IP2 ATG14 ATXN7L2 BEX2 BEX3 BRD8 C1orf216 CAMSAP3 CBX8 CCDC112 CCDC120 CCDC146 CCDC187 CCHCR1 CDC73 CDK18 CORO1A CTAG1A CTAG1B CWF19L2 DCX DTNB ENKD1 ESD EXOC3 FAM107A FAM110A FAM161A FAM50B FAM90A1 FARS2 FMR1 HDAC4 HGS IFT20 KANSL1 KLHL40 LATS1 LENG1 LNX1 MCRS1 MID2 MRPL11 MYBPC2 NDN OIP5 OXNAD1 PBX3 PIK3R3 PNMA5 POLL PPP1R18 PPP2R5D PRPF18 PRPF31 PSMB4 RCOR3 RNF8 SCNM1 SH2D4A SMARCE1 SNAPIN SPATC1L TCEANC THAP7 TLE5 TSGA10IP TTC23 UBTFL1 VEZF1 ZBTB38 ZC2HC1C ZMAT2 ZNF124 ZNF20 ZNF230 ZNF35 ZNF408 ZNF410 ZNF417 ZNF490 ZNF572 ZNF580 ZNF581 ZNF587 ZNF648 ZNF76 ZNF774 ZNF777 ZNF835 ZNF837 ZSCAN26	4 interacting genes: CRK FSD2 GRB2 PLCG2
Entrez ID		123722	2098
HPRD ID		17291	00588
Ensembl ID		ENSG00000186628	ENSG00000139684
Uniprot IDs		A1L4K1 B7ZM05	A0A140VJJ2 P10768
PDB IDs			3FCX
Enriched GO Terms of Interacting Partners?
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