FSD2 and KLHL40

Data Source:
BioGRID (two hybrid)

		FSD2	KLHL40
Description		fibronectin type III and SPRY domain containing 2	kelch like family member 40
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Sarcoplasmic Reticulum Perinuclear Region Of Cytoplasm	Cytoplasm Cul3-RING Ubiquitin Ligase Complex A Band I Band
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Negative Regulation Of Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Skeletal Muscle Fiber Development Skeletal Muscle Fiber Differentiation
Pathways
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Tourette syndrome ( 30818990)
Interacting Genes		94 interacting genes: AQP1 ARFIP2 ATF7IP2 ATG14 ATXN7L2 BEX2 BEX3 BRD8 C1orf216 CAMSAP3 CBX8 CCDC112 CCDC120 CCDC146 CCDC187 CCHCR1 CDC73 CDK18 CORO1A CTAG1A CTAG1B CWF19L2 DCX DTNB ENKD1 ESD EXOC3 FAM107A FAM110A FAM161A FAM50B FAM90A1 FARS2 FMR1 HDAC4 HGS IFT20 KANSL1 KLHL40 LATS1 LENG1 LNX1 MCRS1 MID2 MRPL11 MYBPC2 NDN OIP5 OXNAD1 PBX3 PIK3R3 PNMA5 POLL PPP1R18 PPP2R5D PRPF18 PRPF31 PSMB4 RCOR3 RNF8 SCNM1 SH2D4A SMARCE1 SNAPIN SPATC1L TCEANC THAP7 TLE5 TSGA10IP TTC23 UBTFL1 VEZF1 ZBTB38 ZC2HC1C ZMAT2 ZNF124 ZNF20 ZNF230 ZNF35 ZNF408 ZNF410 ZNF417 ZNF490 ZNF572 ZNF580 ZNF581 ZNF587 ZNF648 ZNF76 ZNF774 ZNF777 ZNF835 ZNF837 ZSCAN26	13 interacting genes: AHNAK C7orf31 CC2D1B FSD2 LMOD3 LRRC29 MCM10 REL SAXO1 TASOR2 VDAC1 ZBED1 ZNF451
Entrez ID		123722	131377
HPRD ID		17291	11058
Ensembl ID		ENSG00000186628	ENSG00000157119
Uniprot IDs		A1L4K1 B7ZM05	A8K5H9 Q2TBA0
PDB IDs			4ASC
Enriched GO Terms of Interacting Partners?
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