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LMTK2 and PTPDC1
Data Source:
BioGRID
(two hybrid)
LMTK2
PTPDC1
Description
lemur tyrosine kinase 2
protein tyrosine phosphatase domain containing 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Early Endosome
Golgi Apparatus
Cytosol
Integral Component Of Plasma Membrane
Integral Component Of Membrane
Growth Cone
Neuronal Cell Body
Receptor Complex
Perinuclear Region Of Cytoplasm
Recycling Endosome
Nucleoplasm
Cytoplasm
Molecular Function
Protein Serine/threonine Kinase Activity
Transmembrane Receptor Protein Tyrosine Kinase Activity
Protein Phosphatase Inhibitor Activity
Protein Binding
ATP Binding
Myosin VI Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Protein Tyrosine Phosphatase Activity
Protein Binding
Protein Tyrosine/serine/threonine Phosphatase Activity
Biological Process
Receptor Recycling
Protein Phosphorylation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Multicellular Organism Development
Axonogenesis
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Peptidyl-tyrosine Phosphorylation
Endocytic Recycling
Negative Regulation Of Phosphoprotein Phosphatase Activity
Transferrin Transport
Positive Regulation Of Kinase Activity
Early Endosome To Late Endosome Transport
Protein Autophosphorylation
Peptidyl-tyrosine Dephosphorylation
Cilium Assembly
Pathways
Drugs
Diseases
GWAS
Gamma glutamyl transferase levels (
29403010
)
Hemoglobin levels (
32327693
)
Prostate cancer (
18264097
)
Birth weight (
31043758
)
Esophageal adenocarcinoma (
24121790
)
Heel bone mineral density (
30598549
)
Height (
20881960
)
Parkinson's disease (
26227905
)
Type 2 diabetes (
30054458
)
Waist-hip ratio (
25673412
)
Waist-to-hip ratio adjusted for body mass index (
25673412
)
Interacting Genes
24 interacting genes:
CDC14A
CDC25C
CDK5
CDK5R1
DUSP14
DUSP19
DUSP29
DUSP6
ILKAP
MTMR6
PPM1A
PPM1F
PPM1K
PPP1CA
PPP1CB
PPP1CC
PPP1R2
PPP3CB
PTPDC1
PTPN12
PTPN6
PTPRR
STYX
TPTE2
8 interacting genes:
AATK
CRKL
ERBB3
ERBB4
LMTK2
MAPK1
MID2
TEX11
Entrez ID
22853
138639
HPRD ID
13994
06689
Ensembl ID
ENSG00000164715
ENSG00000158079
Uniprot IDs
Q8IWU2
A0A087WTF0
A2A3K4
A8K0X7
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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