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LMTK2 and MTMR6
Data Source:
BioGRID
(two hybrid)
LMTK2
MTMR6
Description
lemur tyrosine kinase 2
myotubularin related protein 6
Image
No pdb structure
GO Annotations
Cellular Component
Early Endosome
Golgi Apparatus
Cytosol
Integral Component Of Plasma Membrane
Integral Component Of Membrane
Growth Cone
Neuronal Cell Body
Receptor Complex
Perinuclear Region Of Cytoplasm
Recycling Endosome
Nuclear Envelope
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum-Golgi Intermediate Compartment
Cytosol
Membrane
Ruffle Membrane
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Serine/threonine Kinase Activity
Transmembrane Receptor Protein Tyrosine Kinase Activity
Protein Phosphatase Inhibitor Activity
Protein Binding
ATP Binding
Myosin VI Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Phosphatidylinositol-3-phosphatase Activity
Protein Serine/threonine Phosphatase Activity
Protein Tyrosine Phosphatase Activity
Protein Binding
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Activity
Phosphatidylinositol-3,5-bisphosphate Phosphatase Activity
Biological Process
Receptor Recycling
Protein Phosphorylation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Multicellular Organism Development
Axonogenesis
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Peptidyl-tyrosine Phosphorylation
Endocytic Recycling
Negative Regulation Of Phosphoprotein Phosphatase Activity
Transferrin Transport
Positive Regulation Of Kinase Activity
Early Endosome To Late Endosome Transport
Protein Autophosphorylation
Protein Dephosphorylation
Phosphatidylinositol Biosynthetic Process
Endocytosis
Peptidyl-tyrosine Dephosphorylation
Phosphatidylinositol Dephosphorylation
Pathways
Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS
Gamma glutamyl transferase levels (
29403010
)
Hemoglobin levels (
32327693
)
Prostate cancer (
18264097
)
Metabolite levels (
31628463
)
Triglyceride levels (
32203549
)
Interacting Genes
24 interacting genes:
CDC14A
CDC25C
CDK5
CDK5R1
DUSP14
DUSP19
DUSP29
DUSP6
ILKAP
MTMR6
PPM1A
PPM1F
PPM1K
PPP1CA
PPP1CB
PPP1CC
PPP1R2
PPP3CB
PTPDC1
PTPN12
PTPN6
PTPRR
STYX
TPTE2
14 interacting genes:
AATK
ALKBH4
AMOTL2
ERBB3
ERBB4
LMTK2
MTMR9
MTNR1B
MTUS2
NMI
PTK7
RARG
ROR2
TRIM27
Entrez ID
22853
9107
HPRD ID
13994
11946
Ensembl ID
ENSG00000164715
ENSG00000139505
Uniprot IDs
Q8IWU2
Q9Y217
PDB IDs
2YF0
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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