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PTPDC1 and LMTK2
Data Source:
BioGRID
(two hybrid)
PTPDC1
LMTK2
Description
protein tyrosine phosphatase domain containing 1
lemur tyrosine kinase 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Early Endosome
Golgi Apparatus
Cytosol
Integral Component Of Plasma Membrane
Integral Component Of Membrane
Growth Cone
Neuronal Cell Body
Receptor Complex
Perinuclear Region Of Cytoplasm
Recycling Endosome
Molecular Function
Protein Tyrosine Phosphatase Activity
Protein Binding
Protein Tyrosine/serine/threonine Phosphatase Activity
Protein Serine/threonine Kinase Activity
Transmembrane Receptor Protein Tyrosine Kinase Activity
Protein Phosphatase Inhibitor Activity
Protein Binding
ATP Binding
Myosin VI Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Peptidyl-tyrosine Dephosphorylation
Cilium Assembly
Receptor Recycling
Protein Phosphorylation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Multicellular Organism Development
Axonogenesis
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Peptidyl-tyrosine Phosphorylation
Endocytic Recycling
Negative Regulation Of Phosphoprotein Phosphatase Activity
Transferrin Transport
Positive Regulation Of Kinase Activity
Early Endosome To Late Endosome Transport
Protein Autophosphorylation
Pathways
Drugs
Diseases
GWAS
Birth weight (
31043758
)
Esophageal adenocarcinoma (
24121790
)
Heel bone mineral density (
30598549
)
Height (
20881960
)
Parkinson's disease (
26227905
)
Type 2 diabetes (
30054458
)
Waist-hip ratio (
25673412
)
Waist-to-hip ratio adjusted for body mass index (
25673412
)
Gamma glutamyl transferase levels (
29403010
)
Hemoglobin levels (
32327693
)
Prostate cancer (
18264097
)
Interacting Genes
8 interacting genes:
AATK
CRKL
ERBB3
ERBB4
LMTK2
MAPK1
MID2
TEX11
24 interacting genes:
CDC14A
CDC25C
CDK5
CDK5R1
DUSP14
DUSP19
DUSP29
DUSP6
ILKAP
MTMR6
PPM1A
PPM1F
PPM1K
PPP1CA
PPP1CB
PPP1CC
PPP1R2
PPP3CB
PTPDC1
PTPN12
PTPN6
PTPRR
STYX
TPTE2
Entrez ID
138639
22853
HPRD ID
06689
13994
Ensembl ID
ENSG00000158079
ENSG00000164715
Uniprot IDs
A0A087WTF0
A2A3K4
A8K0X7
Q8IWU2
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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