FH and CCNDBP1

Data Source:
BioGRID (two hybrid)

		FH	CCNDBP1
Description		fumarate hydratase	cyclin D1 binding protein 1
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GO Annotations	Cellular Component	Nucleus Chromosome Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Tricarboxylic Acid Cycle Enzyme Complex Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Nuclear Body
	Molecular Function	Fumarate Hydratase Activity Protein Binding	Protein Binding
	Biological Process	Tricarboxylic Acid Cycle Fumarate Metabolic Process Malate Metabolic Process DNA Repair Homeostasis Of Number Of Cells Within A Tissue Positive Regulation Of Cold-induced Thermogenesis	Cell Cycle Regulation Of Cell Cycle
Pathways		Citric acid cycle (TCA cycle)
Drugs
Diseases		Renal cell carcinoma Multiple cutaneous and uterine leiomyomata Diseases of the tricarboxylic acid cycle, including: Fumarase (FH) deficiency; Succinate dehydrogenase (SDH) deficiency; Alpha-ketoglutarate dehydrogenase (AKGDH) deficiency
GWAS		Daytime sleep phenotypes ( 27126917) Major depressive disorder ( 27479909) Metabolite levels ( 23823483)
Interacting Genes		17 interacting genes: C11orf49 CCDC102B CCDC57 CCNDBP1 DGCR6 EXOSC5 GRB2 H2AZ1 KLHL6 LMNB2 MDH2 PIM1 POLR1C PRKDC SAT1 TNPO2 TTC19	115 interacting genes: ADGRA2 AMPD2 AQP1 ARHGAP22 ATP4B C22orf23 C6orf226 CCDC146 CCDC187 CCND1 CDK18 CDKN2A CFAP65 CNNM3 CUL5 DMRT3 DOCK2 FAM110A FAM126A FAM161A FAM74A4 FH FZD10 GAS2L2 GLIDR GRAP2 GSTK1 HBZ HDAC4 HMGB1 HSPB1 ILF2 IMP3 IRGC LIN37 LNX1 MAP2K2 MOS MRPL15 MRPS9 MTDH NAIF1 NANOS2 NEURL3 NOL7 NSMF NUDCD3 PAXIP1 PIAS2 PIMREG PLEKHA7 PMP2 POLDIP3 POLL PRPF31 PSMB10 PTF1A RARA RARB RBP5 RPL28 RPL39L RPL7L1 RPLP0 RPS28 SASH1 SHFL SIRT6 SLC16A13 SPG7 STK25 SYF2 TCEAL1 TEAD4 TFPT THAP10 THAP7 TMEM120B TRAPPC5 TTC23 TYMSOS WNT11 ZBTB24 ZGPAT ZNF124 ZNF136 ZNF155 ZNF169 ZNF20 ZNF223 ZNF230 ZNF334 ZNF394 ZNF417 ZNF439 ZNF440 ZNF480 ZNF490 ZNF552 ZNF555 ZNF557 ZNF564 ZNF578 ZNF581 ZNF627 ZNF670 ZNF696 ZNF697 ZNF707 ZNF785 ZNF786 ZNF835 ZNF837 ZNRF2P1 ZSCAN26
Entrez ID		2271	23582
HPRD ID		00652	06156
Ensembl ID		ENSG00000091483	ENSG00000166946
Uniprot IDs		A0A0S2Z4C3 P07954	O95273
PDB IDs		3E04 5D6B 5UPP 6EBT	3AY5
Enriched GO Terms of Interacting Partners?
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