MAPK15 and GABARAPL1

Data Source:
BioGRID (pull down, affinity chromatography technology)

		MAPK15	GABARAPL1
Description		mitogen-activated protein kinase 15	GABA type A receptor associated protein like 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Autophagosome Golgi Apparatus Centriole Cell-cell Junction Bicellular Tight Junction Axoneme Cytoplasmic Vesicle Ciliary Basal Body Meiotic Spindle	Autophagosome Membrane Mitochondrion Autophagosome Endoplasmic Reticulum Golgi Apparatus Cytosol Microtubule Cytoplasmic Vesicle Membrane Dendrite Membrane Dendrite Cytoplasm Cell Body
	Molecular Function	Chromatin Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding Kinase Activity SH3 Domain Binding	Protein Binding Tat Protein Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding
	Biological Process	MAPK Cascade Regulation Of COPII Vesicle Coating Cellular Response To DNA Damage Stimulus Endoplasmic Reticulum Organization Positive Regulation Of Cell Population Proliferation Regulation Of Autophagy Negative Regulation Of Cell Migration Positive Regulation Of Telomere Maintenance Via Telomerase Intracellular Signal Transduction Protein Autophosphorylation Positive Regulation Of Telomerase Activity Dopamine Uptake Regulation Of Cilium Assembly Positive Regulation Of Telomere Capping Protein Localization To Ciliary Transition Zone Positive Regulation Of Metaphase/anaphase Transition Of Meiosis I Positive Regulation Of Spindle Assembly	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Macroautophagy Autophagosome Maturation
Pathways			Macroautophagy
Drugs		Acetylsalicylic acid Minocycline Fostamatinib
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		8 interacting genes: CLIC3 CSK GABARAP GABARAPL1 MBP NR3C1 SRC TGFB1I1	73 interacting genes: AHNAK2 AMBRA1 ANK2 ATG13 ATG4A ATG4B ATG4D BNIP3L BSCL2 BSDC1 CALCOCO1 CALCOCO2 CREB3L2 CUL3 DISC1 DVL2 DYNLL1 ERBB2 ERBB3 FUNDC1 HSP90AA1 HSP90AB1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 KXD1 MAPK15 MEFV MLX NEDD4 NFIA OPRK1 OPTN OSBPL3 PBXIP1 PSMB4 PTPRR RABGAP1 RABGAP1L RB1CC1 RCN2 RETREG3 SCYL3 SNCA SQSTM1 SRPK1 SRPK2 STRN3 TAX1BP1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B THAP7 TMEM131 TNIP1 TP53INP1 TRIM21 TRIM32 ULK1 UMAD1 VDR WDFY3 ZBTB22
Entrez ID		225689	23710
HPRD ID		16867	07601
Ensembl ID		ENSG00000181085	ENSG00000139112
Uniprot IDs		Q8TD08	A0A024RAP5 Q9H0R8
PDB IDs			2L8J 2R2Q 5DPT 5LXH 5LXI 6HOI 6HOL
Enriched GO Terms of Interacting Partners?
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