RRAGA and DYNLT1

Data Source:
BioGRID (two hybrid)

		RRAGA	DYNLT1
Description		Ras related GTP binding A	dynein light chain Tctex-type 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Lysosome Lysosomal Membrane Cytosol EGO Complex GATOR1 Complex Gtr1-Gtr2 GTPase Complex	Extracellular Region Mitochondrion Golgi Apparatus Spindle Cytoplasmic Dynein Complex Cytoplasmic Microtubule Lamellipodium Secretory Granule Lumen Neuronal Cell Body Host Cell Axonal Growth Cone Secretory Vesicle Ficolin-1-rich Granule Lumen
	Molecular Function	GTPase Activity Protein Binding GTP Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Protein Heterodimerization Activity Phosphoprotein Binding	Motor Activity Protein Binding Protein C-terminus Binding Identical Protein Binding
	Biological Process	Apoptotic Process Cell Cycle Arrest Cell Death Cellular Response To Starvation Regulation Of Autophagy Negative Regulation Of Autophagy Regulation Of Macroautophagy Protein Ubiquitination Modulation By Virus Of Host Process Positive Regulation Of TOR Signaling Cellular Response To Amino Acid Starvation Cellular Protein Localization Cellular Response To Amino Acid Stimulus Positive Regulation Of TORC1 Signaling	Establishment Of Mitotic Spindle Orientation Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Dendrite Development Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of Mitochondrial Membrane Permeability Regulation Of GTPase Activity Neutrophil Degranulation Viral Entry Into Host Cell Neuron Projection Morphogenesis Negative Regulation Of Neurogenesis Cell Division Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axon Development Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus
Pathways		Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes E3 ubiquitin ligases ubiquitinate target proteins Regulation of PTEN gene transcription Amino acids regulate mTORC1	Neutrophil degranulation
Drugs
Diseases
GWAS
Interacting Genes		6 interacting genes: DYNLT1 IL7R NOL8 RNF152 RPTOR RRAGC	50 interacting genes: ACOX2 ACTN1 APP ARID4B BAG3 BMPR2 CCDC68 DDX54 DHX33 DNAJA2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 DYNC1I2 DYNLT2B DYNLT3 FXR2 HAVCR1 HSPB7 HSPB9 ILF2 KIF2A KLK15 LNX1 NHSL2 NTAQ1 NUP153 NUP62 OLFM3 PELO PITX2 PSMA1 PTGES3L-AARSD1 PTH2R PVR RAD21 RBM14 RRAGA SDCBP SIRPA SVIL TCEANC TROAP TUBA3C TXN UXT VDAC1 XRN2
Entrez ID		10670	6993
HPRD ID		10205	15987
Ensembl ID		ENSG00000155876	ENSG00000146425
Uniprot IDs		Q7L523	P63172
PDB IDs		5X6V 6CES 6EHR 6NZD 6S6A 6S6D 6SB0 6SB2 6U62 6ULG 6WJ2 6WJ3	5JPW
Enriched GO Terms of Interacting Partners?
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