RRAGA and RNF152

Data Source:
BioGRID (pull down, affinity chromatography technology)

		RRAGA	RNF152
Description		Ras related GTP binding A	ring finger protein 152
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Lysosome Lysosomal Membrane Cytosol EGO Complex GATOR1 Complex Gtr1-Gtr2 GTPase Complex	Lysosome Lysosomal Membrane Integral Component Of Organelle Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Protein Heterodimerization Activity Phosphoprotein Binding	Ubiquitin-protein Transferase Activity Protein Binding Small GTPase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Apoptotic Process Cell Cycle Arrest Cell Death Cellular Response To Starvation Regulation Of Autophagy Negative Regulation Of Autophagy Regulation Of Macroautophagy Protein Ubiquitination Modulation By Virus Of Host Process Positive Regulation Of TOR Signaling Cellular Response To Amino Acid Starvation Cellular Protein Localization Cellular Response To Amino Acid Stimulus Positive Regulation Of TORC1 Signaling	Apoptotic Process Positive Regulation Of Autophagy Protein Ubiquitination Cellular Response To Amino Acid Starvation Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Negative Regulation Of TORC1 Signaling
Pathways		Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes E3 ubiquitin ligases ubiquitinate target proteins Regulation of PTEN gene transcription Amino acids regulate mTORC1	E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS			Estimated glomerular filtration rate ( 31015462 30604766) Glomerular filtration rate (creatinine) ( 28452372 26831199)
Interacting Genes		6 interacting genes: DYNLT1 IL7R NOL8 RNF152 RPTOR RRAGC	10 interacting genes: CROCC EBP GJA8 KIR2DL3 RHEB RRAGA TSPAN12 UBE2E1 UBE2N UBE2W
Entrez ID		10670	220441
HPRD ID		10205	11514
Ensembl ID		ENSG00000155876	ENSG00000176641
Uniprot IDs		Q7L523	Q8N8N0
PDB IDs		5X6V 6CES 6EHR 6NZD 6S6A 6S6D 6SB0 6SB2 6U62 6ULG 6WJ2 6WJ3
Enriched GO Terms of Interacting Partners?
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