DDIAS and ACTN4

Data Source:
BioGRID (two hybrid)

		DDIAS	ACTN4
Description		DNA damage induced apoptosis suppressor	actinin alpha 4
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus Cytoplasm	Stress Fiber Extracellular Region Extracellular Space Nucleus Cytoplasm Cytosol Focal Adhesion Actin Cytoskeleton Nuclear Body Platelet Alpha Granule Lumen Pseudopodium Protein-containing Complex Neuron Projection Perinuclear Region Of Cytoplasm Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	Molecular_function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Nucleoside Binding Transcription Coactivator Activity RNA Binding Actin Binding Integrin Binding Calcium Ion Binding Protein Binding Nuclear Receptor Coactivator Activity Chromatin DNA Binding Nuclear Hormone Receptor Binding Protein Homodimerization Activity Retinoic Acid Receptor Binding Ion Channel Binding Protein N-terminus Binding Actin Filament Binding
	Biological Process	Apoptotic Process Mitotic Cell Cycle Arrest Regulation Of DNA Stability Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Response To Hypoxia Platelet Degranulation Protein Transport Vesicle Transport Along Actin Filament Positive Regulation Of Cell Migration Positive Regulation Of Sodium:proton Antiporter Activity Tumor Necrosis Factor-mediated Signaling Pathway Peroxisome Proliferator Activated Receptor Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Cellular Component Movement Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of NIK/NF-kappaB Signaling Regulation Of Nucleic Acid-templated Transcription
Pathways			Platelet degranulation Nephrin family interactions
Drugs
Diseases			Nephrotic syndrome and focal segmental glomerulosclerosis
GWAS			Brain morphology (MOSTest) ( 32665545) Heart rate ( 23583979) Immature fraction of reticulocytes ( 32888494) Logical memory (immediate recall) in mild cognitive impairment ( 29274321) Mean platelet volume ( 32888494) Retinal venular tortuosity ( 31597446) Waist circumference ( 28552196)
Interacting Genes		10 interacting genes: ACLY ACTN1 ACTN4 CBY1 ECM1 EFEMP1 FBLN1 MAF1 MIF4GD PLSCR1	55 interacting genes: ACTC1 ACTN3 ADORA2A ATP6V1B1 ATXN7 BMP7 C14orf119 CAMK2A CAMK2B CAMK2G CDKN2A COIL COL17A1 DDIAS ESR1 GSN HDAC7 HSPB1 INO80 ITGB1 KPNA2 LCMT2 LNX1 LRRC7 MAGI1 MAPK7 MEF2A MEOX2 MICALL2 MYOZ1 MYOZ2 NEB NOS2 NOS3 PDLIM1 POT1 PTGER4 PTPN11 PTPN6 RARA RPS27 SACS SERPINE1 SLC2A4 SLC9A3R2 SORBS2 STAT1 TJP1 TRIM23 TRIM3 TTN TXN UCHL5 USP6NL VDR
Entrez ID		220042	81
HPRD ID		08062	05222
Ensembl ID		ENSG00000165490	ENSG00000130402
Uniprot IDs		B4DMA1 Q8IXT1	A0A0S2Z3G9 O43707
PDB IDs			1WLX 1YDI 2R0O 6O31 6OA6
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?