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ACTN4 and MYOZ2
Data Source:
BioGRID
(two hybrid, two hybrid, two hybrid)
HPRD
(two hybrid)
ACTN4
MYOZ2
Description
actinin alpha 4
myozenin 2
Image
No pdb structure
GO Annotations
Cellular Component
Stress Fiber
Extracellular Region
Extracellular Space
Nucleus
Cytoplasm
Cytosol
Focal Adhesion
Actin Cytoskeleton
Nuclear Body
Platelet Alpha Granule Lumen
Pseudopodium
Protein-containing Complex
Neuron Projection
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Ribonucleoprotein Complex
Actin Cytoskeleton
Sarcomere
Z Disc
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
Nucleoside Binding
Transcription Coactivator Activity
RNA Binding
Actin Binding
Integrin Binding
Calcium Ion Binding
Protein Binding
Nuclear Receptor Coactivator Activity
Chromatin DNA Binding
Nuclear Hormone Receptor Binding
Protein Homodimerization Activity
Retinoic Acid Receptor Binding
Ion Channel Binding
Protein N-terminus Binding
Actin Filament Binding
Actin Binding
Protein Binding
Protein Phosphatase 2B Binding
Telethonin Binding
FATZ Binding
Biological Process
Response To Hypoxia
Platelet Degranulation
Protein Transport
Vesicle Transport Along Actin Filament
Positive Regulation Of Cell Migration
Positive Regulation Of Sodium:proton Antiporter Activity
Tumor Necrosis Factor-mediated Signaling Pathway
Peroxisome Proliferator Activated Receptor Signaling Pathway
Regulation Of Apoptotic Process
Positive Regulation Of Transcription, DNA-templated
Retinoic Acid Receptor Signaling Pathway
Positive Regulation Of Cellular Component Movement
Negative Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of NIK/NF-kappaB Signaling
Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Transcription By RNA Polymerase II
Skeletal Muscle Tissue Development
Biological_process
Skeletal Muscle Fiber Adaptation
Sarcomere Organization
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways
Platelet degranulation
Nephrin family interactions
Drugs
Diseases
Nephrotic syndrome and focal segmental glomerulosclerosis
GWAS
Brain morphology (MOSTest) (
32665545
)
Heart rate (
23583979
)
Immature fraction of reticulocytes (
32888494
)
Logical memory (immediate recall) in mild cognitive impairment (
29274321
)
Mean platelet volume (
32888494
)
Retinal venular tortuosity (
31597446
)
Waist circumference (
28552196
)
HDL cholesterol levels (
32203549
)
Immature fraction of reticulocytes (
32888494
)
PR interval (
32439900
)
Refractive error (
32231278
)
Interacting Genes
55 interacting genes:
ACTC1
ACTN3
ADORA2A
ATP6V1B1
ATXN7
BMP7
C14orf119
CAMK2A
CAMK2B
CAMK2G
CDKN2A
COIL
COL17A1
DDIAS
ESR1
GSN
HDAC7
HSPB1
INO80
ITGB1
KPNA2
LCMT2
LNX1
LRRC7
MAGI1
MAPK7
MEF2A
MEOX2
MICALL2
MYOZ1
MYOZ2
NEB
NOS2
NOS3
PDLIM1
POT1
PTGER4
PTPN11
PTPN6
RARA
RPS27
SACS
SERPINE1
SLC2A4
SLC9A3R2
SORBS2
STAT1
TJP1
TRIM23
TRIM3
TTN
TXN
UCHL5
USP6NL
VDR
18 interacting genes:
ACTN1
ACTN2
ACTN4
CRK
DRICH1
EWSR1
FLNC
HSPB2
LDB3
MBLAC1
MKRN3
MYB
PDLIM3
PPP3CA
PPP3CB
RBPMS
WWOX
ZDHHC17
Entrez ID
81
51778
HPRD ID
05222
05724
Ensembl ID
ENSG00000130402
ENSG00000172399
Uniprot IDs
A0A0S2Z3G9
O43707
Q9NPC6
PDB IDs
1WLX
1YDI
2R0O
6O31
6OA6
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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