PATL1 and LSM6

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		PATL1	LSM6
Description		PAT1 homolog 1, processing body mRNA decay factor	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
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GO Annotations	Cellular Component	P-body Cytosol PML Body Nuclear Speck CCR4-NOT Complex Cytoplasmic Ribonucleoprotein Granule	P-body Nucleus Nucleoplasm U6 SnRNP Nucleolus Sno(s)RNA-containing Ribonucleoprotein Complex Cytoplasm Cytosol Small Nuclear Ribonucleoprotein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Lsm2-8 Complex
	Molecular Function	RNA Binding Protein Binding Poly(U) RNA Binding Poly(G) Binding	RNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA P-body Assembly Exonucleolytic Catabolism Of Deadenylated MRNA	MRNA Splicing, Via Spliceosome MRNA Catabolic Process TRNA Processing RNA Splicing Maturation Of SSU-rRNA Exonucleolytic Catabolism Of Deadenylated MRNA
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease	mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs			Uridine Uridine monophosphate Citric acid
Diseases
GWAS			Malaria ( 31844061) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
Interacting Genes		20 interacting genes: APP FHL3 GOLGA2 KRTAP6-2 LSM2 LSM6 MIR1-2 MIR138-2 MIR15B MIR19B1 MIR19B2 MIR20B MIR21 MIR25 MIR29B2 NFKBID PSMA3 TSC1 WWOX ZMYND12	16 interacting genes: APP CLNS1A LSM1 LSM2 LSM3 LSM5 LSM7 LSM8 MCRS1 PATL1 POLD2 SDCBP SMN1 SNRPD2 SNRPF TARDBP
Entrez ID		219988	11157
HPRD ID		08214	06286
Ensembl ID		ENSG00000166889	ENSG00000164167
Uniprot IDs		Q86TB9	P62312
PDB IDs		2XEQ 2XER 2XES	3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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