EZH1 and ZMYND11

Data Source:
HPRD (in vivo)

		EZH1	ZMYND11
Description		enhancer of zeste 1 polycomb repressive complex 2 subunit	zinc finger MYND-type containing 11
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleoplasm ESC/E(Z) Complex	Nucleus Nucleoplasm Chromosome
	Molecular Function	DNA Binding Chromatin Binding Transcription Corepressor Activity Histone-lysine N-methyltransferase Activity Nucleosomal Histone Binding	Double-stranded DNA Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding Methylated Histone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Chromatin Silencing At Telomere Anatomical Structure Morphogenesis Hippocampus Development Heterochromatin Assembly Positive Regulation Of Transcription By RNA Polymerase II Histone H3-K27 Methylation	Chromatin Organization Cell Cycle Viral Process Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Transcription, DNA-templated Negative Regulation Of JNK Cascade Defense Response To Virus Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Drugs		Tazemetostat
Diseases
GWAS		Height ( 31562340)	Malaria ( 31844061)
Interacting Genes		3 interacting genes: E2F6 EED ZMYND11	24 interacting genes: BMPR1A DYNLL1 E2F6 EMSY ETS2 EZH1 EZH2 H3-3A H3-4 HDAC1 HOXD4 LTBR MAGEC2 MYB NCOR1 PDLIM7 SMAD2 SMAD3 SMARCA4 SRPK1 TAB1 TRAF3 TRAF6 ZHX1
Entrez ID		2145	10771
HPRD ID		03397	09830
Ensembl ID		ENSG00000108799	ENSG00000015171
Uniprot IDs		A0A0A0MSY9 Q92800	B7Z2J6 J3QKD2 Q15326 Q5BJG6 Q5UGI2
PDB IDs			4NS5 5HDA
Enriched GO Terms of Interacting Partners?
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