ZMYND11 and E2F6

Data Source:
HPRD (in vitro, in vivo)

		ZMYND11	E2F6
Description		zinc finger MYND-type containing 11	E2F transcription factor 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome	Chromatin Nucleus Nucleoplasm MLL1 Complex RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Double-stranded DNA Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding Methylated Histone Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity
	Biological Process	Chromatin Organization Cell Cycle Viral Process Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Transcription, DNA-templated Negative Regulation Of JNK Cascade Defense Response To Virus Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G0 To G1 Transition
Pathways			G1/S-Specific Transcription Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Malaria ( 31844061)	Diisocyanate-induced asthma ( 25918132) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Sudden cardiac arrest ( 21658281)
Interacting Genes		24 interacting genes: BMPR1A DYNLL1 E2F6 EMSY ETS2 EZH1 EZH2 H3-3A H3-4 HDAC1 HOXD4 LTBR MAGEC2 MYB NCOR1 PDLIM7 SMAD2 SMAD3 SMARCA4 SRPK1 TAB1 TRAF3 TRAF6 ZHX1	27 interacting genes: APP ARAF BMI1 BRDT CENPU DNMT1 DNMT3L DNTTIP1 E2F1 EPC1 EZH1 EZH2 HMG20B INO80B KRTAP10-7 NFYA PCGF6 PIK3R3 RING1 RYBP SMARCA4 TFDP1 TFDP2 ZBTB17 ZBTB32 ZFPM2 ZMYND11
Entrez ID		10771	1876
HPRD ID		09830	04251
Ensembl ID		ENSG00000015171	ENSG00000169016
Uniprot IDs		B7Z2J6 J3QKD2 Q15326 Q5BJG6 Q5UGI2	A0A0S2Z3K8 O75461 Q53YM3 Q6Q9Z5
PDB IDs		4NS5 5HDA
Enriched GO Terms of Interacting Partners?
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