ZMYND11 and EZH1

Data Source:
HPRD (in vivo)

		ZMYND11	EZH1
Description		zinc finger MYND-type containing 11	enhancer of zeste 1 polycomb repressive complex 2 subunit
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome	Chromosome, Telomeric Region Nucleoplasm ESC/E(Z) Complex
	Molecular Function	Double-stranded DNA Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding Methylated Histone Binding	DNA Binding Chromatin Binding Transcription Corepressor Activity Histone-lysine N-methyltransferase Activity Nucleosomal Histone Binding
	Biological Process	Chromatin Organization Cell Cycle Viral Process Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Transcription, DNA-templated Negative Regulation Of JNK Cascade Defense Response To Virus Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Chromatin Silencing At Telomere Anatomical Structure Morphogenesis Hippocampus Development Heterochromatin Assembly Positive Regulation Of Transcription By RNA Polymerase II Histone H3-K27 Methylation
Pathways
Drugs			Tazemetostat
Diseases
GWAS		Malaria ( 31844061)	Height ( 31562340)
Interacting Genes		24 interacting genes: BMPR1A DYNLL1 E2F6 EMSY ETS2 EZH1 EZH2 H3-3A H3-4 HDAC1 HOXD4 LTBR MAGEC2 MYB NCOR1 PDLIM7 SMAD2 SMAD3 SMARCA4 SRPK1 TAB1 TRAF3 TRAF6 ZHX1	3 interacting genes: E2F6 EED ZMYND11
Entrez ID		10771	2145
HPRD ID		09830	03397
Ensembl ID		ENSG00000015171	ENSG00000108799
Uniprot IDs		B7Z2J6 J3QKD2 Q15326 Q5BJG6 Q5UGI2	A0A0A0MSY9 Q92800
PDB IDs		4NS5 5HDA
Enriched GO Terms of Interacting Partners?
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