ESD and FSD2

Data Source:
BioGRID (two hybrid, two hybrid)

		ESD	FSD2
Description		esterase D	fibronectin type III and SPRY domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Cytosol Cytoplasmic Vesicle Extracellular Exosome	Nucleus Sarcoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Hydrolase Activity, Acting On Ester Bonds S-formylglutathione Hydrolase Activity Identical Protein Binding Methylumbelliferyl-acetate Deacetylase Activity Carboxylic Ester Hydrolase Activity	Protein Binding
	Biological Process	Biological_process Formaldehyde Catabolic Process Glutathione Derivative Biosynthetic Process
Pathways		Glutathione conjugation
Drugs		Glutathione
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Metabolite levels ( 23823483)	HDL cholesterol levels ( 32203549) Tourette syndrome ( 30818990)
Interacting Genes		4 interacting genes: CRK FSD2 GRB2 PLCG2	94 interacting genes: AQP1 ARFIP2 ATF7IP2 ATG14 ATXN7L2 BEX2 BEX3 BRD8 C1orf216 CAMSAP3 CBX8 CCDC112 CCDC120 CCDC146 CCDC187 CCHCR1 CDC73 CDK18 CORO1A CTAG1A CTAG1B CWF19L2 DCX DTNB ENKD1 ESD EXOC3 FAM107A FAM110A FAM161A FAM50B FAM90A1 FARS2 FMR1 HDAC4 HGS IFT20 KANSL1 KLHL40 LATS1 LENG1 LNX1 MCRS1 MID2 MRPL11 MYBPC2 NDN OIP5 OXNAD1 PBX3 PIK3R3 PNMA5 POLL PPP1R18 PPP2R5D PRPF18 PRPF31 PSMB4 RCOR3 RNF8 SCNM1 SH2D4A SMARCE1 SNAPIN SPATC1L TCEANC THAP7 TLE5 TSGA10IP TTC23 UBTFL1 VEZF1 ZBTB38 ZC2HC1C ZMAT2 ZNF124 ZNF20 ZNF230 ZNF35 ZNF408 ZNF410 ZNF417 ZNF490 ZNF572 ZNF580 ZNF581 ZNF587 ZNF648 ZNF76 ZNF774 ZNF777 ZNF835 ZNF837 ZSCAN26
Entrez ID		2098	123722
HPRD ID		00588	17291
Ensembl ID		ENSG00000139684	ENSG00000186628
Uniprot IDs		A0A140VJJ2 P10768	A1L4K1 B7ZM05
PDB IDs		3FCX
Enriched GO Terms of Interacting Partners?
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